Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

GDP-mannose pyrophosphatase NudK

Gene

nudK

Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of GDP-mannose.By similarity

Catalytic activityi

GDP-mannose + H2O = GMP + mannose-1-phosphate.

Cofactori

Mg2+By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciYPSE502800:GH0W-1404-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GDP-mannose pyrophosphatase NudK (EC:3.6.1.-)
Gene namesi
Name:nudK
Ordered Locus Names:YPK_1390
OrganismiYersinia pseudotuberculosis serotype O:3 (strain YPIII)
Taxonomic identifieri502800 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000000721 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198GDP-mannose pyrophosphatase NudKPRO_0000342511Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliB1JSJ3.
SMRiB1JSJ3. Positions 4-188.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini43 – 180138Nudix hydrolasePROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi86 – 10621Nudix boxAdd
BLAST

Sequence similaritiesi

Belongs to the Nudix hydrolase family. NudK subfamily.Curated
Contains 1 nudix hydrolase domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000045855.
OMAiCIRRETE.
OrthoDBiEOG6ZKXR6.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR004385. NDP_pyrophosphatase.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
SUPFAMiSSF55811. SSF55811. 1 hit.
TIGRFAMsiTIGR00052. TIGR00052. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1JSJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVKIENIQC ELLSKNWFKL HKYTFDLKTD EGTSVQQIRE VYDRGNGATI
60 70 80 90 100
LLYNRQQGTV VLIEQFRMPT YVNGNASGML LEACAGLLDN DSPEACIRRE
110 120 130 140 150
AMEETGYQVD KVQKLFEAYM SPGGVTELVY FFAAEYHPDQ KITDEVGVED
160 170 180 190
EVIEVVELPF HDALAMVADG RIKDGKTIML LQYAQIHFFP SSLTPQRC
Length:198
Mass (Da):22,472
Last modified:April 29, 2008 - v1
Checksum:i8CEB6975DAE1A14B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000950 Genomic DNA. Translation: ACA67684.1.
RefSeqiWP_002208529.1. NZ_CP009792.1.

Genome annotation databases

EnsemblBacteriaiACA67684; ACA67684; YPK_1390.
KEGGiypy:YPK_1390.
PATRICi18659964. VBIYerPse127545_1478.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000950 Genomic DNA. Translation: ACA67684.1.
RefSeqiWP_002208529.1. NZ_CP009792.1.

3D structure databases

ProteinModelPortaliB1JSJ3.
SMRiB1JSJ3. Positions 4-188.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA67684; ACA67684; YPK_1390.
KEGGiypy:YPK_1390.
PATRICi18659964. VBIYerPse127545_1478.

Phylogenomic databases

HOGENOMiHOG000045855.
OMAiCIRRETE.
OrthoDBiEOG6ZKXR6.

Enzyme and pathway databases

BioCyciYPSE502800:GH0W-1404-MONOMER.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR004385. NDP_pyrophosphatase.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
SUPFAMiSSF55811. SSF55811. 1 hit.
TIGRFAMsiTIGR00052. TIGR00052. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YPIII.

Entry informationi

Entry nameiNUDK_YERPY
AccessioniPrimary (citable) accession number: B1JSJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: April 29, 2008
Last modified: November 11, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.