Probable thiol peroxidase - Yersinia pseudotuberculosis serotype O:3 (strain YPIII)

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B1JJT3 (B1JJT3_YERPY) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 42. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Probable thiol peroxidase HAMAP-Rule MF_00269
EC=1.11.1.- HAMAP-Rule MF_00269

Gene names

Name:	tpx HAMAP-Rule MF_00269
Ordered Locus Names:	YPK_1903

Organism

Yersinia pseudotuberculosis serotype O:3 (strain YPIII) [Complete proteome] [HAMAP] EMBL ACA68194.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia ›

Protein attributes

Sequence length	167 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function

Has antioxidant activity. Could remove peroxides or H₂O₂ By similarity. HAMAP-Rule MF_00269

Sequence similarities

Belongs to the AhpC/TSA family. Tpx subfamily. HAMAP-Rule MF_00269

Contains 1 thioredoxin domain. HAMAP-Rule MF_00269

Ontologies

Keywords
Molecular function	Antioxidant HAMAP-Rule MF_00269 Oxidoreductase Peroxidase HAMAP-Rule MF_00269
Technical term	3D-structure PDB 2XPD PDB 2XPE PDB 3ZRD PDB 3ZRE Complete proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: HAMAP
Molecular_function	thioredoxin peroxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Domain

149

Thioredoxin By similarity HAMAP-Rule MF_00269

Sequences

Sequence

Length

Mass (Da)

Tools

B1JJT3 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 5021CD65201E7C81
Show »

167

17,592

        10         20         30         40         50         60 
MTQTVHFQGN PVSVAGKLPQ IGDKAKDFTL VAKDLSDVAL SSFAGKRKVL NIFPSIDTGV 

        70         80         90        100        110        120 
CAASVRKFNQ LAGELENTVV LCISSDLPFA QSRFCGAEGL SNVITLSTLR GADFKQAYGV 

       130        140        150        160 
AITEGPLAGL TARAVVVLDG QDNVIYSELV NEITTEPNYD AALAALK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequence of Yersinia pseudotuberculosis YPIII." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: YPIII.
[2]	"Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds." Gabrielsen M., Beckham K.S., Feher V.A., Zetterstrom C.E., Wang D., Muller S., Elofsson M., Amaro R.E., Byron O., Roe A.J. PLoS ONE 7:e32217-e32217(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.74 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000950 Genomic DNA. Translation: ACA68194.1.

RefSeq

YP_001720647.1. NC_010465.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2XPD	X-ray	2.00	A/B/C/D/E/F	1-167	[»]
2XPE	X-ray	2.50	A/B	1-167	[»]
3ZRD	X-ray	1.74	A/B	1-167	[»]
3ZRE	X-ray	2.35	A	1-167	[»]

ProteinModelPortal

SMR

B1JJT3. Positions 2-164.

ModBase

Protein-protein interaction databases

STRING

502800.YPK_1903.
B1JJT3.

Proteomic databases

PRIDE

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

ACA68194; ACA68194; YPK_1903.

GeneID

KEGG

PATRIC

18661130. VBIYerPse127545_2052.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

KO

OMA

ProtClustDB

Family and domain databases

Gene3D

3.40.30.10. 1 hit.

HAMAP

MF_00269. Tpx.

InterPro

IPR018219. Antioxidant_Tpx_CS.
IPR002065. Put_TPX.
IPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view]

Pfam

PF08534. Redoxin. 1 hit.
[Graphical view]

SUPFAM

SSF52833. Thiordxn-like_fd. 1 hit.

PROSITE

PS51352. THIOREDOXIN_2. 1 hit.
PS01265. TPX. 1 hit.
[Graphical view]

ProtoNet

Other

EvolutionaryTrace

Entry information

Entry name

B1JJT3_YERPY

Accession

Primary (citable) accession number: B1JJT3

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info