Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B1JFN3

- GCH4_PSEPW

UniProt

B1JFN3 - GCH4_PSEPW

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Pseudomonas putida (strain W619)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei149 – 1491May be catalytically importantUniRule annotation

    GO - Molecular functioni

    1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciPPUT390235:GHHJ-5236-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:PputW619_5141
    OrganismiPseudomonas putida (strain W619)
    Taxonomic identifieri390235 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000720: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 295295GTP cyclohydrolase FolE2PRO_0000372034Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi390235.PputW619_5141.

    Structurei

    3D structure databases

    ProteinModelPortaliB1JFN3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase IV family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1469.
    HOGENOMiHOG000247517.
    KOiK09007.
    OMAiWISLIER.
    OrthoDBiEOG6X6RBH.

    Family and domain databases

    HAMAPiMF_01527_B. GTP_cyclohydrol_B.
    InterProiIPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view]
    PfamiPF02649. GCHY-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1JFN3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSLTLPDIA AQKHQHATPL AWVGMCGIAL PVHFDGRSVA AMADAGVSLE    50
    DGSSRGIHMS RLYLSLERLE RQSLTPLAIR QILADFLASH EGLSHAAYLR 100
    LTFDHLLKRP ALVSPLAGWK SYSITVDAKI ENGMFHVELS VRVPYSSTCP 150
    CSAALARQLI QQQFQADFSG QAINREAVLE WLGSSHGIVA TPHSQRSLAE 200
    VNVRLGDRLE VLPVTELIDR IEASLGTAVQ TAVKRADEQA FALANGQNLM 250
    FCEDAARRLH QALQQMDWAK AFKLRVEHAE SLHAHDAVAA SQWQW 295
    Length:295
    Mass (Da):32,440
    Last modified:April 29, 2008 - v1
    Checksum:iE37B1B66BC21746C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000949 Genomic DNA. Translation: ACA75617.1.
    RefSeqiYP_001751986.1. NC_010501.1.

    Genome annotation databases

    EnsemblBacteriaiACA75617; ACA75617; PputW619_5141.
    GeneIDi6114143.
    KEGGippw:PputW619_5141.
    PATRICi19960264. VBIPsePut93764_5176.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000949 Genomic DNA. Translation: ACA75617.1 .
    RefSeqi YP_001751986.1. NC_010501.1.

    3D structure databases

    ProteinModelPortali B1JFN3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 390235.PputW619_5141.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACA75617 ; ACA75617 ; PputW619_5141 .
    GeneIDi 6114143.
    KEGGi ppw:PputW619_5141.
    PATRICi 19960264. VBIPsePut93764_5176.

    Phylogenomic databases

    eggNOGi COG1469.
    HOGENOMi HOG000247517.
    KOi K09007.
    OMAi WISLIER.
    OrthoDBi EOG6X6RBH.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci PPUT390235:GHHJ-5236-MONOMER.

    Family and domain databases

    HAMAPi MF_01527_B. GTP_cyclohydrol_B.
    InterProi IPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view ]
    Pfami PF02649. GCHY-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: W619.

    Entry informationi

    Entry nameiGCH4_PSEPW
    AccessioniPrimary (citable) accession number: B1JFN3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 5, 2009
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3