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B1JDZ8 (PQQC_PSEPW) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase
EC=1.3.3.11
Alternative name(s):
Coenzyme PQQ synthesis protein C
Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name:pqqC
Ordered Locus Names:PputW619_4825
OrganismPseudomonas putida (strain W619) [Complete proteome] [HAMAP]
Taxonomic identifier390235 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length251 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family.

Ontologies

Keywords
   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 251251Pyrroloquinoline-quinone synthase HAMAP MF_00654
PRO_1000131179

Sequences

Sequence LengthMass (Da)Tools
B1JDZ8 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 7934B6515C6E88BD

FASTA25129,122
        10         20         30         40         50         60 
MSEALPLSPA EFEQALRAKG AYYHIHHPYH VAMYEGRATR EQIQGWVANR FYYQVNIPMK 

        70         80         90        100        110        120 
DAAILANCPD REVRREWIQR LLDHDGAPGE DGGIEAWLRL GQAVGLDPDQ LRSQELVLPG 

       130        140        150        160        170        180 
VRFAVDAYVN FARRASWQEA ASSSLTELFA PQIHQSRLDS WPQHYPWIDP AGYEYFRTRL 

       190        200        210        220        230        240 
GQARRDVEHG LTITLQHYTT RAAQERMLEI LQFKLDILWS MLDAMSMAYE LHRPPYHTVT 

       250 
QQRVWHKGIA L

« Hide

References

[1]"Complete sequence of Pseudomonas putida W619."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Taghavi S., Vangronsveld D., van der Lelie D., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: W619.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000949 Genomic DNA. Translation: ACA75301.1.
RefSeqYP_001751670.1. NC_010501.1.

3D structure databases

ProteinModelPortalB1JDZ8.
SMRB1JDZ8. Positions 7-246.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1JDZ8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6113815.
GenomeReviewsGene locus PputW619_4825 in contig CP000949_GR.
KEGGppw:PputW619_4825.
PATRIC19959603. VBIPsePut93764_4857.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry namePQQC_PSEPW
AccessionPrimary (citable) accession number: B1JDZ8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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