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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

PputW619_3512

Organism
Pseudomonas putida (strain W619)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciPPUT390235:GHHJ-3563-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported (EC:1.2.4.2Imported)
Gene namesi
Ordered Locus Names:PputW619_3512Imported
OrganismiPseudomonas putida (strain W619)Imported
Taxonomic identifieri390235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000720: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi390235.PputW619_3512.

Structurei

3D structure databases

ProteinModelPortaliB1JAV6.
SMRiB1JAV6. Positions 90-943.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

B1JAV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQESVMQRMW ESAHLSGGNA AYVEELYELY LHDPNAVPEE WRTYFQKLPA
60 70 80 90 100
DGSTATDVSH STIRDHFVLL AKNQRRAQPV SAGSVSSEHE KKQVEVLRLI
110 120 130 140 150
QAYRMRGHQA AKLDPLGLWQ RPAPVDLSIN HYGLTNADLD TTFRAGDLYI
160 170 180 190 200
GKEEASLREI VEALQKTYCR TIGAEFTHIV DSEQRSWFQQ RLESVRGRPD
210 220 230 240 250
FSADVQAHLL ERVTAGEGLE KYLGTKYPGT KRFGLEGGES LIPMLDEMIQ
260 270 280 290 300
RSGSYGTKEV VIGMAHRGRL NVLVNTFGKN PRELFDEFEG KKMNELGSGD
310 320 330 340 350
VKYHQGFSSN VMTTGGEVHL AMAFNPSHLE IVSPVVEGSV RARQDRRNDT
360 370 380 390 400
AGDKVLPISI HGDAAFAGQG VVMETFQMSQ TRGFKTGGTV HIVINNQVGF
410 420 430 440 450
TISNPLDSRS TEYATDVAKM IQAPILHVNG DDPEAVLFVT QLAIDYRMQF
460 470 480 490 500
KRDVVIDLVC YRRRGHNEAD EPNGTQPLMY QQISKQRTTR ELYAEALIQA
510 520 530 540 550
GRIDAERAQA KIDEYRNALD NGLHVVKSLV KEPNRELFVD WRPYLGHAWT
560 570 580 590 600
ARHDTRFDLK TLQDLSAKLL ELPEGFVVQR QVSKIYEDRQ KMQAGGLPIN
610 620 630 640 650
WGYAETMAYA TLQFEGHPIR MTGQDIGRGT FSHRHAVLHN QKDASTYVPL
660 670 680 690 700
QNLFPGQPRF DLYDSFLSEE AVLAFEYGYS TTTPNALVIW EAQFGDFANG
710 720 730 740 750
AQVVIDQFIT SGEHKWGRLC GLTMLLPHGY EGQGPEHSSA RLERYLQLCA
760 770 780 790 800
EHNIQVCVPT TPAQIYHLLR RQVIRPLRKP LIVLTPKSLL RHKLAVSTLE
810 820 830 840 850
DLAEGSFQTV IPEIDTLDPA KVERLVLCGG KVYYDLLEKR RAEGREDIAI
860 870 880 890 900
VRIEQLYPFP EDDLVDILAP YTNLKHAVWC QEEPMNQGAW YSSQHHMRRI
910 920 930 940
LGRHNKALVL EYAGRDASAA PACGYASKHA EQQEKLLQDA FTV
Length:943
Mass (Da):106,408
Last modified:April 29, 2008 - v1
Checksum:iE9BC015E56D970D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000949 Genomic DNA. Translation: ACA73995.1.
RefSeqiYP_001750364.1. NC_010501.1.

Genome annotation databases

EnsemblBacteriaiACA73995; ACA73995; PputW619_3512.
GeneIDi6112470.
KEGGippw:PputW619_3512.
PATRICi19956892. VBIPsePut93764_3534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000949 Genomic DNA. Translation: ACA73995.1.
RefSeqiYP_001750364.1. NC_010501.1.

3D structure databases

ProteinModelPortaliB1JAV6.
SMRiB1JAV6. Positions 90-943.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi390235.PputW619_3512.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA73995; ACA73995; PputW619_3512.
GeneIDi6112470.
KEGGippw:PputW619_3512.
PATRICi19956892. VBIPsePut93764_3534.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciPPUT390235:GHHJ-3563-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: W619Imported.

Entry informationi

Entry nameiB1JAV6_PSEPW
AccessioniPrimary (citable) accession number: B1JAV6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: March 4, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.