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Protein

Probable 5-dehydro-4-deoxyglucarate dehydratase

Gene

PputW619_2814

Organism
Pseudomonas putida (strain W619)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2.UniRule annotation

Pathwayi: D-glucarate degradation

This protein is involved in step 2 of the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable 5-dehydro-4-deoxyglucarate dehydratase (PputW619_2814)
This subpathway is part of the pathway D-glucarate degradation, which is itself part of Carbohydrate acid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2,5-dioxopentanoate from D-glucarate, the pathway D-glucarate degradation and in Carbohydrate acid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Enzyme and pathway databases

BioCyciPPUT390235:G1GBA-2890-MONOMER
UniPathwayiUPA00564; UER00628

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 5-dehydro-4-deoxyglucarate dehydrataseUniRule annotation (EC:4.2.1.41UniRule annotation)
Alternative name(s):
5-keto-4-deoxy-glucarate dehydrataseUniRule annotation
Short name:
KDGDHUniRule annotation
Gene namesi
Ordered Locus Names:PputW619_2814
OrganismiPseudomonas putida (strain W619)
Taxonomic identifieri390235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000720 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001322721 – 303Probable 5-dehydro-4-deoxyglucarate dehydrataseAdd BLAST303

Proteomic databases

PRIDEiB1J9C7

Interactioni

Protein-protein interaction databases

STRINGi390235.PputW619_2814

Structurei

3D structure databases

ProteinModelPortaliB1J9C7
SMRiB1J9C7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DapA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105UVJ Bacteria
COG0329 LUCA
HOGENOMiHOG000173605
KOiK01707
OMAiRNRKKGY
OrthoDBiPOG091H00C1

Family and domain databases

CDDicd00951 KDGDH, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00694 KDGDH, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR002220 DapA-like
IPR017655 Dehydro-deoxyglucarate_dehyd
PANTHERiPTHR12128 PTHR12128, 1 hit
PfamiView protein in Pfam
PF00701 DHDPS, 1 hit
PIRSFiPIRSF001365 DHDPS, 1 hit
SMARTiView protein in SMART
SM01130 DHDPS, 1 hit
TIGRFAMsiTIGR03249 KdgD, 1 hit

Sequencei

Sequence statusi: Complete.

B1J9C7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPQELKSIL SHGLLSFPVT DFNAQGDFNQ AGYIKRLEWL APYGASALFA
60 70 80 90 100
AGGTGEFFSL AASEYSQVIK TAVDTCAKSV PILAGVGGST RQAIEYAQEA
110 120 130 140 150
ERLGAKGLLL LPHYLTEASQ DGVAAHVEAV CKSVNIGVVV YNRNVCRLNA
160 170 180 190 200
DLLEKLAERC PNLIGYKDGL GDIELMVSIR RRLGDRFSYL GGLPTAEVYA
210 220 230 240 250
AAYKALGVPV YSSAVFNFIP KTAMDFYHAI ARDDHATVGK LIDDFFLPYL
260 270 280 290 300
DIRNRKAGYA VSIVKAGAKI AGYDAGPVRT PLTDLTAEEY EMLAALMDKM

GPQ
Length:303
Mass (Da):32,700
Last modified:April 29, 2008 - v1
Checksum:i160D54F3E1A2C06C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000949 Genomic DNA Translation: ACA73306.1
RefSeqiWP_012314664.1, NC_010501.1

Genome annotation databases

EnsemblBacteriaiACA73306; ACA73306; PputW619_2814
KEGGippw:PputW619_2814

Similar proteinsi

Entry informationi

Entry nameiKDGD_PSEPW
AccessioniPrimary (citable) accession number: B1J9C7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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