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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Pseudomonas putida (strain W619)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPPUT390235:G1GBA-4753-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:PputW619_4621
OrganismiPseudomonas putida (strain W619)
Taxonomic identifieri390235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000720 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001337411 – 364Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST364

Interactioni

Protein-protein interaction databases

STRINGi390235.PputW619_4621

Structurei

3D structure databases

ProteinModelPortaliB1J5X5
SMRiB1J5X5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

B1J5X5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREETREQPA PLRSGLTTGS CATATSLAAA RLLLTGVSTD AVSITLPKGK
60 70 80 90 100
VVQMRLEFCR REDERAEAGT LKDAGDDPDV THGALLYSQV RLQDEPGIRF
110 120 130 140 150
VAGVGVGTVT RPGLVLAVGE PAINPVPRRM ISEHLQQLAD DCAYRGGFEV
160 170 180 190 200
TVNVKGGEQL ALKTMNPRLG ILGGLSILGT SGIVRPFSCA AYIASIHQGI
210 220 230 240 250
DVAHTNGYTH IAACTGNASE DTMRRVYGLP EIALIEMGDF VGAVLKHLRK
260 270 280 290 300
VPVPRLSLCG GFGKISKLAA GHMDLHSRHS SIDLPQLAGW AADIGADADL
310 320 330 340 350
QAAIMAANTS QQALALAHAA GIALGDAVCA HALAFARSVV PAQVQVEVFA
360
IDRQGGIVGK AGMQ
Length:364
Mass (Da):38,032
Last modified:April 29, 2008 - v1
Checksum:i4FD1EE55DE5354C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000949 Genomic DNA Translation: ACA75101.1
RefSeqiWP_012316420.1, NC_010501.1

Genome annotation databases

EnsemblBacteriaiACA75101; ACA75101; PputW619_4621
KEGGippw:PputW619_4621

Similar proteinsi

Entry informationi

Entry nameiCBID_PSEPW
AccessioniPrimary (citable) accession number: B1J5X5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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