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B1J2J5 (AROB_PSEPW) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:PputW619_0388
OrganismPseudomonas putida (strain W619) [Complete proteome] [HAMAP]
Taxonomic identifier390235 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP-Rule MF_00110

Cofactor

Divalent metal cations By similarity.

NAD By similarity.

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP-Rule MF_00110

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

chorismate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3653653-dehydroquinate synthase HAMAP-Rule MF_00110
PRO_1000094574

Sequences

Sequence LengthMass (Da)Tools
B1J2J5 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 2D6F12A9DEF5D82D

FASTA36539,548
        10         20         30         40         50         60 
MQTLKVDLGE RSYPIYIGEG LLDQPELLAP HIAGRQIAIV SNETVAPLYL ERLSKALGAY 

        70         80         90        100        110        120 
SVLPVILPDG EAHKNWETLQ LIFDGLLTAR HDRRTTVVAL GGGVIGDMAG FAAACYQRGV 

       130        140        150        160        170        180 
DFIQVPTTLL SQVDSSVGGK TGINHPLGKN MVGAFYQPNA VLIDTTTLNT LPERELSAGL 

       190        200        210        220        230        240 
AEVIKYGLIC DKPFLGWLED NIKALRALEP AALTEAIQRS CAAKAAVVGA DERESGVRAT 

       250        260        270        280        290        300 
LNLGHTFGHA IETHMGYGVW LHGEAVAAGT VMALEMSMRL GWIDQSERDR AIRLLQDAGL 

       310        320        330        340        350        360 
PVVPPQEMTP AHFMEHMAVD KKVIDGRLRL VLLRQMGEAV VTDDYPKEIL QATLSADYRA 


IVAQL

« Hide

References

[1]"Complete sequence of Pseudomonas putida W619."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Taghavi S., Vangronsveld D., van der Lelie D., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: W619.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000949 Genomic DNA. Translation: ACA70894.1.
RefSeqYP_001747263.1. NC_010501.1.

3D structure databases

ProteinModelPortalB1J2J5.
ModBaseSearch...

Protein-protein interaction databases

STRING390235.PputW619_0388.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA70894; ACA70894; PputW619_0388.
GeneID6109168.
KEGGppw:PputW619_0388.
PATRIC19950501. VBIPsePut93764_0392.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHOG000007970.
KOK01735.
OMAVMALEMS.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycPPUT390235:GHHJ-389-MONOMER.
UniPathwayUPA00053; UER00085.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. aroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_PSEPW
AccessionPrimary (citable) accession number: B1J2J5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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