Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B1J0T9 (CYNS_ECOLC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cyanate hydratase

Short name=Cyanase
EC=4.2.1.104
Alternative name(s):
Cyanate hydrolase
Cyanate lyase
Gene names
Name:cynS
Ordered Locus Names:EcolC_3285
OrganismEscherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) [Complete proteome] [HAMAP]
Taxonomic identifier481805 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length156 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide By similarity. HAMAP-Rule MF_00535

Catalytic activity

Cyanate + HCO3- + 2 H+ = NH3 + 2 CO2. HAMAP-Rule MF_00535

Sequence similarities

Belongs to the cyanase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcyanate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

cyanate hydratase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 156156Cyanate hydratase HAMAP-Rule MF_00535
PRO_1000081862

Sites

Active site961 By similarity
Active site991 By similarity
Active site1221 By similarity

Sequences

Sequence LengthMass (Da)Tools
B1J0T9 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 63AA586490ED4D3D

FASTA15617,054
        10         20         30         40         50         60 
MIQSQINRNI RLDLADAILL SKAKKDLSFA EIADGTGLAE AFVTEALLGQ QALPADAARL 

        70         80         90        100        110        120 
VGAKLDLDED SILLLQMIPL RGCIDDRIPT DPTMYRFYEM LQVYGTTLKA LVHEKFGDGI 

       130        140        150 
ISAINFKLDV KKVADPEGGE CAVITLDGKY LPTKPF 

« Hide

References

[1]"Complete sequence of Escherichia coli C str. ATCC 8739."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Ingram L., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 8739 / DSM 1576 / Crooks.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000946 Genomic DNA. Translation: ACA78907.1.
RefSeqYP_001726234.1. NC_010468.1.

3D structure databases

ProteinModelPortalB1J0T9.
SMRB1J0T9. Positions 1-156.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING481805.EcolC_3285.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA78907; ACA78907; EcolC_3285.
GeneID6066978.
KEGGecl:EcolC_3285.
PATRIC18229610. VBIEscCol82905_3508.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1513.
HOGENOMHOG000043436.
KOK01725.
OMAAIDFKMD.
OrthoDBEOG63FW2F.
ProtClustDBPRK02866.

Enzyme and pathway databases

BioCycECOL481805:GI3G-3357-MONOMER.

Family and domain databases

Gene3D1.10.260.40. 1 hit.
3.30.1160.10. 1 hit.
HAMAPMF_00535. Cyanate_hydrat.
InterProIPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamPF02560. Cyanate_lyase. 1 hit.
[Graphical view]
PIRSFPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSPR01693. CYANASE.
SUPFAMSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsTIGR00673. cynS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYNS_ECOLC
AccessionPrimary (citable) accession number: B1J0T9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 29, 2008
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families