B1IYJ2 (CITX_ECOLC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
EC=2.7.7.61

Alternative name(s):
Apo-ACP nucleodityltransferase
Holo-ACP synthase
Holo-citrate lyase synthase

Gene names

Name:	citX
Ordered Locus Names:	EcolC_3030

Organism

Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) [Complete proteome] [HAMAP]

Taxonomic identifier

481805 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein By similarity. HAMAP MF_00398
Catalytic activity	2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-[acyl-carrier-protein] + diphosphate. HAMAP MF_00398
Sequence similarities	Belongs to the CitX family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	prosthetic group biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	holo-citrate lyase synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 183	183	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase HAMAP MF_00398		PRO_1000080329

Sequences

	Sequence		Length	Mass (Da)
	B1IYJ2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 22B3643BDABE06C8	FASTA	183	20,286
	10 20 30 40 50 60 MHLLPELASH HAVSIPELLV SRDERQARQH VWLKRHPVPL VSFTVVAPGP IKDCEVTRRI 70 80 90 100 110 120 FNHGVTALRA LAAKQGWQIQ EQAALVSASG PEGMLSIAAP ARDLKLATIE LEHSHPLGRL 130 140 150 160 170 180 WDIDVLTPEG EILSRRDYSL PPRRCLLCEQ SAAVCARGKT HQLTDLLNRM EALLNDVDAC NVN

References

[1]

"Complete sequence of Escherichia coli C str. ATCC 8739." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Ingram L., Richardson P. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8739 / DSM 1576 / Crooks.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000946 Genomic DNA. Translation: ACA78654.1.
RefSeq	YP_001725981.1. NC_010468.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B1IYJ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000009231; EBESCP00000008915; EBESCG00000008294.
GeneID	6065423.
GenomeReviews	Gene locus EcolC_3030 in contig CP000946_GR.
KEGG	ecl:EcolC_3030.
PATRIC	18229064. VBIEscCol82905_3236.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000009839.
HOGENOM	HBG698187.
OMA	PIGRLMD.
ProtClustDB	PRK01392.
Enzyme and pathway databases
BioCyc	ECOL481805:ECOLC_3030-MONOMER.
Family and domain databases
HAMAP	MF_00398. CitX. [Tree]
InterPro	IPR005551. CitX. [Graphical view]
KO	K05964.
Pfam	PF03802. CitX. 1 hit. [Graphical view]
TIGRFAMs	TIGR03124. Citrate_citX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CITX_ECOLC

Accession

Primary (citable) accession number: B1IYJ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program