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B1IX88 (FCTA_ECOLC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Formyl-coenzyme A transferase
Short name=Formyl-CoA transferase
EC=2.8.3.16
Gene names
Name:frc
Ordered Locus Names:EcolC_1295
OrganismEscherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) [Complete proteome] [HAMAP]
Taxonomic identifier481805 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate By similarity. HAMAP MF_00742

Catalytic activity

Formyl-CoA + oxalate = formate + oxalyl-CoA. HAMAP MF_00742

Pathway

Metabolic intermediate degradation; oxalate degradation; CO(2) and formate from oxalate: step 1/2. HAMAP MF_00742

Subunit structure

Homodimer By similarity. HAMAP MF_00742

Sequence similarities

Belongs to the CaiB/BaiF CoA-transferase family.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionformyl-CoA transferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Formyl-coenzyme A transferase HAMAP MF_00742
PRO_1000083472

Sites

Active site1691Nucleophile By similarity
Binding site961Coenzyme A By similarity

Sequences

Sequence LengthMass (Da)Tools
B1IX88 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 97F7FA4001073301

FASTA41645,828
        10         20         30         40         50         60 
MSTPLQGIKV LDFTGVQSGP SCTQMLAWFG ADVIKIERPG VGDVTRHQLR DIPDIDALYF 

        70         80         90        100        110        120 
TMLNSNKRSI ELNTKTAEGK EVMEKLIREA DILVENFHPG AIDHMGFTWE HIQEINPRLI 

       130        140        150        160        170        180 
FGSIKGFDEC SPYVNVKAYE NVAQAAGGAA STTGFWDGPP LVSAAALGDS NTGMHLLIGL 

       190        200        210        220        230        240 
LAALLHREKT GRGQRVTMSM QDAVLNLCRV KLRDQQRLDK LGYLEEYPQY PNGTFGDAVP 

       250        260        270        280        290        300 
RGGNAGGGGQ PGWILKCKGW ETDPNAYIYF TIQEQNWENT CKAIGKPEWI TDPAYSTAHA 

       310        320        330        340        350        360 
RQPHIFDIFA EIEKYTVTID KHEAVAYLTQ FDIPCAPVLS MKEISLDPSL RQSGSVVEVE 

       370        380        390        400        410 
QPLRGKYLTV GCPMKFSAFT PDIKAAPLLG EHTAAVLQEL GYSDDEIAAM KQNHAI

« Hide

References

[1]"Complete sequence of Escherichia coli C str. ATCC 8739."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Ingram L., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 8739 / DSM 1576 / Crooks.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000946 Genomic DNA. Translation: ACA76961.1.
RefSeqYP_001724288.1. NC_010468.1.

3D structure databases

ProteinModelPortalB1IX88.
SMRB1IX88. Positions 2-416.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1IX88.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000008768; EBESCP00000008452; EBESCG00000007831.
GeneID6068617.
GenomeReviewsGene locus EcolC_1295 in contig CP000946_GR.
KEGGecl:EcolC_1295.
PATRIC18225299. VBIEscCol82905_1385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000009654.
HOGENOMHBG659028.
OMADEWANDP.
ProtClustDBPRK05398.

Enzyme and pathway databases

BioCycECOL481805:ECOLC_1295-MONOMER.

Family and domain databases

HAMAPMF_00742. Formyl-CoA_transfer.
[Tree]
InterProIPR003673. CoA-Trfase_fam_III.
IPR023606. CoA-Trfase_III_dom.
IPR017659. Formyl-CoA_transferase.
[Graphical view]
Gene3DG3DSA:3.40.50.10540. CoA-Trfase_fam_III. 1 hit.
KOK07749.
PANTHERPTHR11837. CAIB_BAIF. 1 hit.
PfamPF02515. CoA_transf_3. 1 hit.
[Graphical view]
SUPFAMSSF89796. CoA-Trfase_fam_III. 1 hit.
TIGRFAMsTIGR03253. Oxalate_frc. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFCTA_ECOLC
AccessionPrimary (citable) accession number: B1IX88
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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