Reviewed,
UniProtKB/Swiss-Prot B1IUF8 (NAGZ_ECOLC)
Last modified
January 19, 2010.
Version 13.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Beta-hexosaminidase EC=3.2.1.52 Alternative name(s): N-acetyl-beta-glucosaminidase Beta-N-acetylhexosaminidase | ||||
| Gene names |
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| Organism | Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 481805 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 341 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides By similarity. HAMAP MF_00364 |
| Catalytic activity | Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. HAMAP MF_00364 |
| Pathway | Cell wall biogenesis; peptidoglycan recycling. HAMAP MF_00364 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00364. |
| Sequence similarities | Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis |
| Cellular component | Cytoplasm |
| Molecular function | Glycosidase Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell divisionInferred from electronic annotation. Source: UniProtKB-KW cellular cell wall organizationInferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW peptidoglycan turnoverInferred from electronic annotation. Source: HAMAP regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | beta-N-acetylhexosaminidase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 341 | 341 | Beta-hexosaminidase HAMAP MF_00364 | PRO_1000079574 | |||||
Sites | |||||||||
| Active site | 248 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of Escherichia coli C str. ATCC 8739." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. Richardson P.Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000946 Genomic DNA. Translation: ACA78125.1. |
| RefSeq | YP_001725452.1. |
3D structure databases | |
| SMR | B1IUF8. Positions 1-334. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 6067647. |
| GenomeReviews | Gene locus EcolC_2494 in contig CP000946_GR. |
| KEGG | ecl:EcolC_2494. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG617255. |
| OMA | SACGIDL. |
Family and domain databases | |
| HAMAP | MF_00364. NagZ. [Tree] |
| InterPro | IPR019800. Glyco_hydro_3_AS. IPR001764. Glyco_hydro_3_N. IPR017853. Glyco_hydro_catalytic_core. [Graphical view] |
| Gene3D | G3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit. |
| Pfam | PF00933. Glyco_hydro_3. 1 hit. [Graphical view] |
| PROSITE | PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NAGZ_ECOLC | ||||||||
| Accession | Primary (citable) accession number: B1IUF8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Glycosyl hydrolases Classification of glycosyl hydrolase families and list of entries |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


