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B1IRM5 (UXAC_ECOLC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uronate isomerase
EC=5.3.1.12
Alternative name(s):
Glucuronate isomerase
Uronic isomerase
Gene names
Name:uxaC
Ordered Locus Names:EcolC_0608
OrganismEscherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) [Complete proteome] [HAMAP]
Taxonomic identifier481805 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucuronate = D-fructuronate. HAMAP-Rule MF_00675

D-galacturonate = D-tagaturonate. HAMAP-Rule MF_00675

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00675

Sequence similarities

Belongs to the uronate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglucuronate isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Uronate isomerase HAMAP-Rule MF_00675
PRO_1000082961

Sequences

Sequence LengthMass (Da)Tools
B1IRM5 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 9E51AA7B88411281

FASTA47053,987
        10         20         30         40         50         60 
MTPFMTEDFL LDTEFARRLY HDYAKDQPIF DYHCHLPPQQ IAEDYRFKNL YDIWLKGDHY 

        70         80         90        100        110        120 
KWRAMRTNGV AERLCTGDAS DREKFDAWAA TVPHTIGNPL YHWTHLELRR PFGITGKLLS 

       130        140        150        160        170        180 
PSTADEIWNE CNELLAQDNF SARGIMQQMN VKMVGTTDDP IDSLEHHAEI AKDGSFTIKV 

       190        200        210        220        230        240 
LPSWRPDKAF NIEQATFNDY MAKLGEVSDT DIRRFADLQT ALTKRLDHFA AHGCKVSDHA 

       250        260        270        280        290        300 
LDVVMFAEAN EAELDSILAR RLAGETLSEH EVAQFKTAVL VFLGAEYARR GWVQQYHIGA 

       310        320        330        340        350        360 
LRNNNLRQFK LLGPDVGFDS INDRPMAEEL SKLLSKQNEE NLLPKTILYC LNPRDNEVLG 

       370        380        390        400        410        420 
TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM ERQMTQLAQL GLLSRFVGML TDSRSFLSYT 

       430        440        450        460        470 
RHEYFRRILC QMIGRWVEAG EAPADINLLG EMVKNICFNN ARDYFAIELN

« Hide

References

[1]"Complete sequence of Escherichia coli C str. ATCC 8739."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Ingram L., Richardson P.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 8739 / DSM 1576 / Crooks.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000946 Genomic DNA. Translation: ACA76284.1.
RefSeqYP_001723611.1. NC_010468.1.

3D structure databases

ProteinModelPortalB1IRM5.
SMRB1IRM5. Positions 4-468.
ModBaseSearch...

Protein-protein interaction databases

STRING481805.EcolC_0608.

Proteomic databases

PRIDEB1IRM5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA76284; ACA76284; EcolC_0608.
GeneID6065566.
KEGGecl:EcolC_0608.
PATRIC18223770. VBIEscCol82905_0643.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1904.
HOGENOMHOG000224075.
KOK01812.
OMAGNPIYHW.
ProtClustDBPRK02925.

Enzyme and pathway databases

BioCycECOL481805:GI3G-620-MONOMER.
UniPathwayUPA00246.

Family and domain databases

Gene3D1.10.2020.10. 1 hit.
HAMAPMF_00675. UxaC.
InterProIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUXAC_ECOLC
AccessionPrimary (citable) accession number: B1IRM5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 29, 2008
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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