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Protein

Ribulokinase

Gene

araB

Organism
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.UniRule annotation

Pathwayi: L-arabinose degradation via L-ribulose

This protein is involved in step 2 of the subpathway that synthesizes D-xylulose 5-phosphate from L-arabinose (bacterial route).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. L-arabinose isomerase (araA)
  2. Ribulokinase (araB)
  3. no protein annotated in this organism
This subpathway is part of the pathway L-arabinose degradation via L-ribulose, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-xylulose 5-phosphate from L-arabinose (bacterial route), the pathway L-arabinose degradation via L-ribulose and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Arabinose catabolism, Carbohydrate metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL481805:GI3G-3676-MONOMER.
UniPathwayiUPA00145; UER00566.

Names & Taxonomyi

Protein namesi
Recommended name:
RibulokinaseUniRule annotation (EC:2.7.1.16UniRule annotation)
Gene namesi
Name:araBUniRule annotation
Ordered Locus Names:EcolC_3594
OrganismiEscherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Taxonomic identifieri481805 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 566566RibulokinasePRO_1000081680Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi481805.EcolC_3594.

Structurei

3D structure databases

ProteinModelPortaliB1IRB5.
SMRiB1IRB5. Positions 2-564.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribulokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EF1. Bacteria.
COG1069. LUCA.
HOGENOMiHOG000236883.
KOiK00853.
OMAiACTMLPI.

Family and domain databases

HAMAPiMF_00520. Ribulokinase. 1 hit.
InterProiIPR018485. Carb_kinase_FGGY_C.
IPR005929. Ribulokinase.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01234. L-ribulokinase. 1 hit.

Sequencei

Sequence statusi: Complete.

B1IRB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIAIGLDFG SDSVRALAVD CASGEEIATS VEWYPRWQKG QFCDAPNNQF
60 70 80 90 100
RHHPRDYIES MEAALKTVLA ELSVEQRAAV VGIGVDSTGS TPAPIDADGN
110 120 130 140 150
VLALRPEFAE NPNAMFVLWK DHTAVEEAEE ITRLCHAPGN VDYSRYIGGI
160 170 180 190 200
YSSEWFWAKI LHVTRQDSAV AQSAASWIEL CDWVPALLSG TTRPQDIRRG
210 220 230 240 250
RCSAGHKSLW HESWGGLPPA SFFDELDPIL NRHLPSPLFT DTWTADIPVG
260 270 280 290 300
TLCPEWAQRL GLPESVVISG GAFDCHMGAV GAGAQPNALV KVIGTSTCDI
310 320 330 340 350
LIADKQSVGE RAVKGICGQV DGSVVPGFIG LEAGQSAFGD IYAWFGRVLS
360 370 380 390 400
WPLEQLAAQH PELKAQINAS QKQLLPALTE AWAKNPSLDH LPVVLDWFNG
410 420 430 440 450
RRSPNANQRL KGVITDLNLA TDAPLLFGGL IAATAFGARA IMECFTDQGI
460 470 480 490 500
AVNNVMALGG IARKNQVIMQ ACCDVLNRPL QIVASDQCCA LGAAIFAAVA
510 520 530 540 550
AKVHADIPSA QQKMASAVEK TLQPRSEQAQ RFEQLYRRYQ QWAMSAEQHY
560
LPTSAPAQAA QAVATL
Length:566
Mass (Da):61,114
Last modified:April 29, 2008 - v1
Checksum:i6A0C37B0D17B03FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000946 Genomic DNA. Translation: ACA79208.1.
RefSeqiWP_000951777.1. NC_010468.1.

Genome annotation databases

EnsemblBacteriaiACA79208; ACA79208; EcolC_3594.
KEGGiecl:EcolC_3594.
PATRICi18230288. VBIEscCol82905_3838.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000946 Genomic DNA. Translation: ACA79208.1.
RefSeqiWP_000951777.1. NC_010468.1.

3D structure databases

ProteinModelPortaliB1IRB5.
SMRiB1IRB5. Positions 2-564.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi481805.EcolC_3594.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA79208; ACA79208; EcolC_3594.
KEGGiecl:EcolC_3594.
PATRICi18230288. VBIEscCol82905_3838.

Phylogenomic databases

eggNOGiENOG4105EF1. Bacteria.
COG1069. LUCA.
HOGENOMiHOG000236883.
KOiK00853.
OMAiACTMLPI.

Enzyme and pathway databases

UniPathwayiUPA00145; UER00566.
BioCyciECOL481805:GI3G-3676-MONOMER.

Family and domain databases

HAMAPiMF_00520. Ribulokinase. 1 hit.
InterProiIPR018485. Carb_kinase_FGGY_C.
IPR005929. Ribulokinase.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01234. L-ribulokinase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiARAB_ECOLC
AccessioniPrimary (citable) accession number: B1IRB5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 29, 2008
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.