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Protein

Glutaminase

Gene

glsA

Organism
Clostridium botulinum (strain Okra / Type B1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei61SubstrateUniRule annotation1
Binding sitei113SubstrateUniRule annotation1
Binding sitei158SubstrateUniRule annotation1
Binding sitei165SubstrateUniRule annotation1
Binding sitei189SubstrateUniRule annotation1
Binding sitei241SubstrateUniRule annotation1
Binding sitei259Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:CLD_1766
OrganismiClostridium botulinum (strain Okra / Type B1)
Taxonomic identifieri498213 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000008541 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001156951 – 305GlutaminaseAdd BLAST305

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB1IKM0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B1IKM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRLLKTIIE NNRKWISEGK VASYIPELSK MDKNLLGISV CTLGGEEYWE
60 70 80 90 100
GDAEVKFTIQ SISKIVTLML AIIDNGEDYV FSKVGMEPTE TAFNSIVNLE
110 120 130 140 150
AKESHKPINP MINAGAIVVA SMVAGKDSDE KFDRILKFTR KISGNNDIDI
160 170 180 190 200
NLNVYESEKE TGHRNRALAY FMKSTGALKG NVEEILDVYF KQCSIEITCK
210 220 230 240 250
DLARIGVMLA NDGVSPYTGD RIVPRHVARI VKTIMVTCGM YDASGNFAVH
260 270 280 290 300
IGIPAKSGVG GGIIACAPRR MGIGVLGTAL DEKGNSIAGT KILEELSKQL

DLSIF
Length:305
Mass (Da):33,286
Last modified:April 29, 2008 - v1
Checksum:iB1C813A8CD343350
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000939 Genomic DNA. Translation: ACA46530.1.
RefSeqiWP_003399984.1. NC_010516.1.

Genome annotation databases

EnsemblBacteriaiACA46530; ACA46530; CLD_1766.
KEGGicbb:CLD_1766.
PATRICi19405976. VBICloBot127283_2892.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000939 Genomic DNA. Translation: ACA46530.1.
RefSeqiWP_003399984.1. NC_010516.1.

3D structure databases

ProteinModelPortaliB1IKM0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA46530; ACA46530; CLD_1766.
KEGGicbb:CLD_1766.
PATRICi19405976. VBICloBot127283_2892.

Phylogenomic databases

HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_CLOBK
AccessioniPrimary (citable) accession number: B1IKM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: November 2, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.