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B1ICY4

- WHIA_STRPI

UniProt

B1ICY4 - WHIA_STRPI

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Protein

Putative sporulation transcription regulator WhiA

Gene

whiA

Organism
Streptococcus pneumoniae (strain Hungary19A-6)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

May be required for sporulation.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi272 – 30332H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. endonuclease activity Source: InterPro

GO - Biological processi

  1. regulation of sporulation Source: UniProtKB-HAMAP
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSPNE487214:GHY0-1647-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiAUniRule annotation
Gene namesi
Name:whiAUniRule annotation
Ordered Locus Names:SPH_1678
OrganismiStreptococcus pneumoniae (strain Hungary19A-6)
Taxonomic identifieri487214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002163: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Putative sporulation transcription regulator WhiAPRO_0000376580Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi487214.SPH_1678.

Family & Domainsi

Sequence similaritiesi

Belongs to the WhiA transcriptional regulatory family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR00647. MG103. 1 hit.

Sequencei

Sequence statusi: Complete.

B1ICY4 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSFTVAVKEE ILGQHHLSWH ELSAIIKMSG NIGLSTSGLT LSVVTENAKL
60 70 80 90 100
ARHLYESFLH FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA
110 120 130 140 150
DSFFGLETGI DEAILSDEEA GRAYLCGAFL ANGSIRDPES GKYQLEISSV
160 170 180 190 200
YLDHAQGIAS LLQQFLLDAK VLERKKGAVT YLQRAEDIMD FLIVIGAMQA
210 220 230 240 250
RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN NISKIKDIMG
260 270 280 290 300
LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA

DEL
Length:303
Mass (Da):34,119
Last modified:April 29, 2008 - v1
Checksum:iAA07C116DB5C7900
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000936 Genomic DNA. Translation: ACA35599.1.
RefSeqiYP_001694969.1. NC_010380.1.

Genome annotation databases

EnsemblBacteriaiACA35599; ACA35599; SPH_1678.
GeneIDi6028204.
KEGGispv:SPH_1678.
PATRICi19693462. VBIStrPne34925_1681.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000936 Genomic DNA. Translation: ACA35599.1 .
RefSeqi YP_001694969.1. NC_010380.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 487214.SPH_1678.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACA35599 ; ACA35599 ; SPH_1678 .
GeneIDi 6028204.
KEGGi spv:SPH_1678.
PATRICi 19693462. VBIStrPne34925_1681.

Phylogenomic databases

eggNOGi COG1481.
HOGENOMi HOG000040187.
KOi K09762.
OMAi HKFMLDA.
OrthoDBi EOG68WR87.

Enzyme and pathway databases

BioCyci SPNE487214:GHY0-1647-MONOMER.

Family and domain databases

Gene3Di 3.10.28.10. 1 hit.
HAMAPi MF_01420. HTH_type_WhiA.
InterProi IPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view ]
Pfami PF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55608. SSF55608. 1 hit.
TIGRFAMsi TIGR00647. MG103. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Streptococcus pneumoniae strain Hungary 19A-6."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hungary19A-6.

Entry informationi

Entry nameiWHIA_STRPI
AccessioniPrimary (citable) accession number: B1ICY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: April 29, 2008
Last modified: October 1, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3