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Protein
Submitted name:

Response regulator

Gene

SPH_0494

Organism
Streptococcus pneumoniae (strain Hungary19A-6)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. phosphorelay signal transduction system Source: InterPro
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSPNE487214:GHY0-488-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Response regulatorImported
Gene namesi
Ordered Locus Names:SPH_0494Imported
OrganismiStreptococcus pneumoniae (strain Hungary19A-6)Imported
Taxonomic identifieri487214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002163: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi487214.SPH_0494.

Structurei

3D structure databases

ProteinModelPortaliB1I9I6.
SMRiB1I9I6. Positions 140-205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH luxR-type DNA-binding domain.UniRule annotation
Contains HTH luxR-type DNA-binding domain.SAAS annotation
Contains response regulatory domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG2197.
HOGENOMiHOG000034813.
KOiK11618.
OMAiKSHVGRI.
OrthoDBiEOG69GZGV.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1I9I6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKILLVDDHE MVRLGLKSYF DLQDDVEVVG EASNGSQGID LALELRPDVI
60 70 80 90 100
VMDIVMPEMN GIDATLAILK EWPEAKILIV TSYLDNEKIM PVLDAGAKGY
110 120 130 140 150
MLKTSSADEL LHAVSKVAAG ELAIEQEVSK KVEYHRNHME LHEELTARER
160 170 180 190 200
DVLQLIAKGY ENQRIADDLF ISLKTVKTHV SNILAKLEVS DRTQAAVYAF
210
QHHLVGHEEF
Length:210
Mass (Da):23,562
Last modified:April 29, 2008 - v1
Checksum:iDA9357028D340FDC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000936 Genomic DNA. Translation: ACA36981.1.
RefSeqiYP_001693899.1. NC_010380.1.

Genome annotation databases

EnsemblBacteriaiACA36981; ACA36981; SPH_0494.
GeneIDi6028118.
KEGGispv:SPH_0494.
PATRICi19691082. VBIStrPne34925_0496.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000936 Genomic DNA. Translation: ACA36981.1.
RefSeqiYP_001693899.1. NC_010380.1.

3D structure databases

ProteinModelPortaliB1I9I6.
SMRiB1I9I6. Positions 140-205.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi487214.SPH_0494.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA36981; ACA36981; SPH_0494.
GeneIDi6028118.
KEGGispv:SPH_0494.
PATRICi19691082. VBIStrPne34925_0496.

Phylogenomic databases

eggNOGiCOG2197.
HOGENOMiHOG000034813.
KOiK11618.
OMAiKSHVGRI.
OrthoDBiEOG69GZGV.

Enzyme and pathway databases

BioCyciSPNE487214:GHY0-488-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Streptococcus pneumoniae strain Hungary 19A-6."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hungary19A-6Imported.

Entry informationi

Entry nameiB1I9I6_STRPI
AccessioniPrimary (citable) accession number: B1I9I6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 7, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.