Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Streptococcus pneumoniae (strain Hungary19A-6)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei312 – 3121UniRule annotation
Active sitei426 – 4261UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSPNE487214:GHY0-2220-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:SPH_2257
OrganismiStreptococcus pneumoniae (strain Hungary19A-6)
Taxonomic identifieri487214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002163 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Glucose-6-phosphate isomerasePRO_1000125766Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi487214.SPH_2257.

Structurei

3D structure databases

ProteinModelPortaliB1I9D8.
SMRiB1I9D8. Positions 3-449.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1I9D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHIKFDYSK VLDKFVAPHE VEYMQSQVTA ADELIRKGTG AGSDFLGWLD
60 70 80 90 100
LPEKYDREEF DRILKAAEQI KSDSDVLVVI GIGGSYLGAK AAIDFLNHHF
110 120 130 140 150
ANLQTKEERK APQILYAGNS ISSTYLADLV EYVADKDFSV NVISKSGTTT
160 170 180 190 200
EPAIAFRVFK ELLVKKYGQE EANKRIYATT DRQKGAVKVE ADANGWGTFV
210 220 230 240 250
VPDDIGGRFS VLTAVGLLPI AASGADIKAL MEGANAARKD YTSDKISENE
260 270 280 290 300
AYQYAAVRNI LYRKGYATEI LVNYEPSLQY FSEWWKQLAG ESEGKDQKGI
310 320 330 340 350
YPTSANFSTD LHSLGQFIQE GTRIMFETVV RVDKPRKNVL IPTLEEDLDG
360 370 380 390 400
LGYLQGKDVD FVNKKATDGV LLAHTDGDVP NMYVTLPEQD AFTLGYTIYF
410 420 430 440
FELAIALSGY LNAINPFDQP GVEAYKRNMF ALLGKPGFEE LSKELNARL
Length:449
Mass (Da):49,878
Last modified:April 29, 2008 - v1
Checksum:i563518A955D0C1E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000936 Genomic DNA. Translation: ACA36198.1.
RefSeqiWP_000018262.1. NC_010380.1.
YP_001695433.1. NC_010380.1.

Genome annotation databases

EnsemblBacteriaiACA36198; ACA36198; SPH_2257.
KEGGispv:SPH_2257.
PATRICi19694667. VBIStrPne34925_2231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000936 Genomic DNA. Translation: ACA36198.1.
RefSeqiWP_000018262.1. NC_010380.1.
YP_001695433.1. NC_010380.1.

3D structure databases

ProteinModelPortaliB1I9D8.
SMRiB1I9D8. Positions 3-449.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi487214.SPH_2257.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA36198; ACA36198; SPH_2257.
KEGGispv:SPH_2257.
PATRICi19694667. VBIStrPne34925_2231.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciSPNE487214:GHY0-2220-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Streptococcus pneumoniae strain Hungary 19A-6."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hungary19A-6.

Entry informationi

Entry nameiG6PI_STRPI
AccessioniPrimary (citable) accession number: B1I9D8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: May 27, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.