Reviewed, UniProtKB/Swiss-Prot B1I863 (GALT_STRPI)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	SPH_1968

Organism

Streptococcus pneumoniae (strain Hungary19A-6) [Complete proteome] [HAMAP]

Taxonomic identifier

487214 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 493	493	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_1000129495

Sequences

	Sequence		Length	Mass (Da)
	B1I863-1 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: DA4165A9E278B499	FASTA	493	56,148
	10 20 30 40 50 60 MILVDKFVTH VISESSFEEM DRIYLTNRVL ARVGEGVLEV ETNLDKLIDL KDQLVEEAVR 70 80 90 100 110 120 LETIEDSQTA REILGTELMD LVTPCPSQVN RDFWEAYAYS PEQAIEDFYQ LSQKNDYIKL 130 140 150 160 170 180 KAIAKNIAYR VPSDYGELEI TINLSKPEKD PKEIAAAKLV QASNYPQCQL CLENEGYHGR 190 200 210 220 230 240 VNHPARTNHR IIRFEMVGQE WGFQYSPYAY FNEHCIFLDG QHRPMAISRQ SFERLLAIVE 250 260 270 280 290 300 QFPGYFAGSN ADLPIVGGSI LTHDHYQGGR HVFPMELAPL QKTFRFAGFE QVKAGIIKWP 310 320 330 340 350 360 MSVLRLTSDS KEDLINLADK IFQEWRQYSD SSVQILAETD GTPHHTITPI ARKRDGQFEL 370 380 390 400 410 420 DLVLRDNQTS AEHPDGIYHP HKDVQHIKKE NIGLIEVMGL AILPPRLKEE VEQVASYLVG 430 440 450 460 470 480 EAVTVADYHQ EWADQLKSQH PDLTDKEKAL AIVKDSVGAI FVRVLEDAGV YKQTEQGQAA 490 FMRFVEQVGI SLD

References

[1]	"Complete sequence of Streptococcus pneumoniae strain Hungary 19A-6." Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000936 Genomic DNA. Translation: ACA37395.1.
RefSeq	YP_001695219.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6028304.
GenomeReviews	Gene locus SPH_1968 in contig CP000936_GR.
KEGG	spv:SPH_1968.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EHYQGGR.
Family and domain databases
HAMAP	MF_00571. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. galT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_STRPI

Accession

Primary (citable) accession number: B1I863

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 29, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)