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B1I863 (GALT_STRPI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Galactose-1-phosphate uridylyltransferase

Short name=Gal-1-P uridylyltransferase
EC=2.7.7.12
Alternative name(s):
UDP-glucose--hexose-1-phosphate uridylyltransferase
Gene names
Name:galT
Ordered Locus Names:SPH_1968
OrganismStreptococcus pneumoniae (strain Hungary19A-6) [Complete proteome] [HAMAP]
Taxonomic identifier487214 [NCBI]
Taxonomic lineageBacteriaFirmicutesLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571

Pathway

Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571

Subcellular location

Cytoplasm Potential HAMAP MF_00571.

Sequence similarities

Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Galactose metabolism
   Cellular componentCytoplasm
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgalactose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionUDP-glucose:hexose-1-phosphate uridylyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 493493Galactose-1-phosphate uridylyltransferase HAMAP MF_00571
PRO_1000129495

Sequences

Sequence LengthMass (Da)Tools
B1I863 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: DA4165A9E278B499

FASTA49356,148
        10         20         30         40         50         60 
MILVDKFVTH VISESSFEEM DRIYLTNRVL ARVGEGVLEV ETNLDKLIDL KDQLVEEAVR 

        70         80         90        100        110        120 
LETIEDSQTA REILGTELMD LVTPCPSQVN RDFWEAYAYS PEQAIEDFYQ LSQKNDYIKL 

       130        140        150        160        170        180 
KAIAKNIAYR VPSDYGELEI TINLSKPEKD PKEIAAAKLV QASNYPQCQL CLENEGYHGR 

       190        200        210        220        230        240 
VNHPARTNHR IIRFEMVGQE WGFQYSPYAY FNEHCIFLDG QHRPMAISRQ SFERLLAIVE 

       250        260        270        280        290        300 
QFPGYFAGSN ADLPIVGGSI LTHDHYQGGR HVFPMELAPL QKTFRFAGFE QVKAGIIKWP 

       310        320        330        340        350        360 
MSVLRLTSDS KEDLINLADK IFQEWRQYSD SSVQILAETD GTPHHTITPI ARKRDGQFEL 

       370        380        390        400        410        420 
DLVLRDNQTS AEHPDGIYHP HKDVQHIKKE NIGLIEVMGL AILPPRLKEE VEQVASYLVG 

       430        440        450        460        470        480 
EAVTVADYHQ EWADQLKSQH PDLTDKEKAL AIVKDSVGAI FVRVLEDAGV YKQTEQGQAA 

       490 
FMRFVEQVGI SLD 

« Hide

References

[1]"Complete sequence of Streptococcus pneumoniae strain Hungary 19A-6."
Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Hungary19A-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000936 Genomic DNA. Translation: ACA37395.1.
RefSeqYP_001695219.1. NC_010380.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB1I863.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000024280; EBSTRP00000023446; EBSTRG00000024280.
GeneID6028304.
GenomeReviewsGene locus SPH_1968 in contig CP000936_GR.
KEGGspv:SPH_1968.
PATRIC19694073. VBIStrPne34925_1987.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000027103.
HOGENOMHBG337915.
OMAHYFIGSN.
ProtClustDBPRK05270.

Enzyme and pathway databases

BioCycSPNE487214:SPH_1968-MONOMER.

Family and domain databases

HAMAPMF_00571. GalP_UDP_trans.
[Tree]
InterProIPR000766. GalP_uridyl_Trfase_II.
IPR023425. GalP_uridyl_Trfase_II_CS.
IPR005850. GalP_Utransf_C.
IPR005849. GalP_Utransf_N.
[Graphical view]
KOK00965.
PfamPF02744. GalP_UDP_tr_C. 1 hit.
PF01087. GalP_UDP_transf. 1 hit.
[Graphical view]
PIRSFPIRSF006005. GalT_BS. 1 hit.
TIGRFAMsTIGR01239. GalT_2. 1 hit.
PROSITEPS01163. GAL_P_UDP_TRANSF_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGALT_STRPI
AccessionPrimary (citable) accession number: B1I863
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families