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Protein
Submitted name:

Ribosomal RNA small subunit methyltransferase B

Gene

sun

Organism
Streptococcus pneumoniae (strain Hungary19A-6)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei276S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei304S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei323S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei376NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ribosomal RNA small subunit methyltransferase BImported (EC:2.1.1.-Imported)
Gene namesi
Name:sunImported
Ordered Locus Names:SPH_1843Imported
OrganismiStreptococcus pneumoniae (strain Hungary19A-6)Imported
Taxonomic identifieri487214 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000002163 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB1I7J7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 435SAM_MT_RSMB_NOPInterPro annotationAdd BLAST278

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni253 – 259S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH

Family and domain databases

Gene3Di1.10.940.10, 1 hit
InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

B1I7J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVETARSL ALAVLEDVFV NQAYSNIALN KHLKGSQLLA ADKGLVTELV
60 70 80 90 100
YGTVARKLTL EWYLSHFIED RDQLDSWLYV LLLMSAYQLR YLDKIPDHAV
110 120 130 140 150
VNEAVELAKL RKKGSEKLVN ALLRRILREG WPDISSIKRK NKRDSIAYSL
160 170 180 190 200
PVWLVAKLKE EYGEERAKAI FESLLVRNKA SIRVTDLSRK EEIQALLEAN
210 220 230 240 250
NSLLATTGLV KEQGHFAGHN LFADGAITIQ DESSQLVAPT LDLQGDERVL
260 270 280 290 300
DACAAPGGKT AHIASYLTTG QVTALDLYDH KLDLIQENAQ RLGVADRVQT
310 320 330 340 350
QKLDARKVHE FFDQDSFDKI LVDAPCSGIG LLRRKPDIKY NKETADFASL
360 370 380 390 400
QEIQLEILGS VCQILGKGGI ITYSTCTIVS EENFQVVKAF LESHPEFEQV
410 420 430
KLEHECKDIM KDGCILITPE LYGSDGFFIS QFRKISD
Length:437
Mass (Da):48,997
Last modified:April 29, 2008 - v1
Checksum:i7DA19747A1669820
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000936 Genomic DNA Translation: ACA35917.1

Genome annotation databases

EnsemblBacteriaiACA35917; ACA35917; SPH_1843
KEGGispv:SPH_1843

Similar proteinsi

Entry informationi

Entry nameiB1I7J7_STRPI
AccessioniPrimary (citable) accession number: B1I7J7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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