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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Desulforudis audaxviator (strain MP104C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCDES477974:G1GAD-2257-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Daud_2181
OrganismiDesulforudis audaxviator (strain MP104C)
Taxonomic identifieri477974 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeCandidatus Desulforudis
Proteomesi
  • UP000008544 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953591 – 563Arginine--tRNA ligaseAdd BLAST563

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi477974.Daud_2181

Structurei

3D structure databases

ProteinModelPortaliB1I6Q5
SMRiB1I6Q5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi137 – 147"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiHGMSTRQ
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B1I6Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYLLAGLRA GIERALRGAV EAARPDLGLD SGTAIPPFTV EVPREKNHGD
60 70 80 90 100
FATNLALLLT KPARRSPRQI AEILVSHLSL PELLVKEVTV AGPGFINFRL
110 120 130 140 150
DPNWLHGVLP EIETWGEHYG RRNLGGGRKV QVEFVSANPT GLLHMGNARG
160 170 180 190 200
AALGDSIAAL LSFVGFDVTR EFYVNDAGHQ VENLALSMEA RYFQALGRDW
210 220 230 240 250
PVPEDGYHGE DLIDTAGRFV AEHGDRFASG DPDERRGALL RFALEEKLAA
260 270 280 290 300
MRATLESFGV RYDVWFSEQS LYDRGVVGET LELLKKRGHL YERDGALWFK
310 320 330 340 350
AGAFGGDKDE VLVRRNGVPT YFAADIAYHK DKYDRGFDWV INVWGADHHG
360 370 380 390 400
HVPRMKGALA ALGYDPDALD VVIMQLVRLY RGGEIVRMSK RTGRYVTLDE
410 420 430 440 450
LLEEVGRDAA RYFFVTRGAD SHLDFDLDLA KSRTNENPVY YIQYAHARIS
460 470 480 490 500
SIFRQLEERG RTAPGYRKIP DVTLLKEEAE RALIRRLADF PDEVAQAAYD
510 520 530 540 550
LAPHRIAHYV HDLAGLFHHF YNAHRVLGAG DGLEEARLML VNCTRVVLRN
560
ALTLLGVSAP ERM
Length:563
Mass (Da):62,937
Last modified:April 29, 2008 - v1
Checksum:i54D6DD596F32BCEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000860 Genomic DNA Translation: ACA60668.1
RefSeqiWP_012303243.1, NC_010424.1

Genome annotation databases

EnsemblBacteriaiACA60668; ACA60668; Daud_2181
KEGGidau:Daud_2181

Similar proteinsi

Entry informationi

Entry nameiSYR_DESAP
AccessioniPrimary (citable) accession number: B1I6Q5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome