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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

Daud_1591

Organism
Desulforudis audaxviator (strain MP104C)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei287S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei314S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei332S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei385NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Ordered Locus Names:Daud_1591Imported
OrganismiDesulforudis audaxviator (strain MP104C)Imported
Taxonomic identifieri477974 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeCandidatus Desulforudis
Proteomesi
  • UP000008544 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi477974.Daud_1591.

Structurei

3D structure databases

ProteinModelPortaliB1I502.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini173 – 450SAM_MT_RSMB_NOPInterPro annotationAdd BLAST278

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

B1I502-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVSAREIA LHVLKAVEAD GAYANLALNR ALEEFRPSKL DRAFATELAY
60 70 80 90 100
GTLRTLNTLD WIVSRYLQQP LGDQTVWSRN ILRLGAYQLF YMDKVPAGAA
110 120 130 140 150
CFEAVELAKK YGTPGTARFV NGVLRNVARH KDELQFPDPE TDLVTHISLK
160 170 180 190 200
YFHPTWLVKR WLTELGPEET IALCQANNTI PPNTIRVNTL RVDRDSLAVR
210 220 230 240 250
LEQEGLTVRK TRFAPEGLEI GGFVSMRALP SFQQGLFQIQ DESSMLVAHA
260 270 280 290 300
VNPARGVRIL DACSAPGGKT THLAQLMENE GIIKALDIHQ HKLKLVSDNC
310 320 330 340 350
RRLGIDNVET ELLDARDLPG EFEGWADFVL VDAPCSGLGV LRRRPDARWR
360 370 380 390 400
KEPGQITGLV RLQEAILAGA AQCVRAGGVL VYSTCTITYE ENLGQVQSFL
410 420 430 440 450
AHHPDFLLEN LRPFLPAGLG EEQMARGYLE IFPHTHEGMD GFFIARMRRR

HL
Length:452
Mass (Da):50,540
Last modified:April 29, 2008 - v1
Checksum:i2C5FAF281BB9190C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000860 Genomic DNA. Translation: ACA60093.1.
RefSeqiWP_012302674.1. NC_010424.1.

Genome annotation databases

EnsemblBacteriaiACA60093; ACA60093; Daud_1591.
KEGGidau:Daud_1591.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB1I502_DESAP
AccessioniPrimary (citable) accession number: B1I502
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: June 7, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported