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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

Daud_1591

Organism
Desulforudis audaxviator (strain MP104C)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei287S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei314S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei332S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei385NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCDES477974:G1GAD-1649-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Ordered Locus Names:Daud_1591Imported
OrganismiDesulforudis audaxviator (strain MP104C)Imported
Taxonomic identifieri477974 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeCandidatus Desulforudis
Proteomesi
  • UP000008544 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi477974.Daud_1591

Structurei

3D structure databases

ProteinModelPortaliB1I502
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini173 – 450SAM_MT_RSMB_NOPInterPro annotationAdd BLAST278

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni263 – 269S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH
OrthoDBiPOG091H02E2

Family and domain databases

Gene3Di1.10.940.10, 1 hit
InterProiView protein in InterPro
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

B1I502-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVSAREIA LHVLKAVEAD GAYANLALNR ALEEFRPSKL DRAFATELAY
60 70 80 90 100
GTLRTLNTLD WIVSRYLQQP LGDQTVWSRN ILRLGAYQLF YMDKVPAGAA
110 120 130 140 150
CFEAVELAKK YGTPGTARFV NGVLRNVARH KDELQFPDPE TDLVTHISLK
160 170 180 190 200
YFHPTWLVKR WLTELGPEET IALCQANNTI PPNTIRVNTL RVDRDSLAVR
210 220 230 240 250
LEQEGLTVRK TRFAPEGLEI GGFVSMRALP SFQQGLFQIQ DESSMLVAHA
260 270 280 290 300
VNPARGVRIL DACSAPGGKT THLAQLMENE GIIKALDIHQ HKLKLVSDNC
310 320 330 340 350
RRLGIDNVET ELLDARDLPG EFEGWADFVL VDAPCSGLGV LRRRPDARWR
360 370 380 390 400
KEPGQITGLV RLQEAILAGA AQCVRAGGVL VYSTCTITYE ENLGQVQSFL
410 420 430 440 450
AHHPDFLLEN LRPFLPAGLG EEQMARGYLE IFPHTHEGMD GFFIARMRRR

HL
Length:452
Mass (Da):50,540
Last modified:April 29, 2008 - v1
Checksum:i2C5FAF281BB9190C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000860 Genomic DNA Translation: ACA60093.1
RefSeqiWP_012302674.1, NC_010424.1

Genome annotation databases

EnsemblBacteriaiACA60093; ACA60093; Daud_1591
KEGGidau:Daud_1591

Similar proteinsi

Entry informationi

Entry nameiB1I502_DESAP
AccessioniPrimary (citable) accession number: B1I502
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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