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Protein

Glutamate racemase

Gene

murI

Organism
Desulforudis audaxviator (strain MP104C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei73Proton donor/acceptorUniRule annotation1
Active sitei184Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciCDES477974:G1GAD-1564-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:Daud_1508
OrganismiDesulforudis audaxviator (strain MP104C)
Taxonomic identifieri477974 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeCandidatus Desulforudis
Proteomesi
  • UP000008544 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001140401 – 273Glutamate racemaseAdd BLAST273

Interactioni

Protein-protein interaction databases

STRINGi477974.Daud_1508

Structurei

3D structure databases

ProteinModelPortaliB1I4X2
SMRiB1I4X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni10 – 11Substrate bindingUniRule annotation2
Regioni42 – 43Substrate bindingUniRule annotation2
Regioni74 – 75Substrate bindingUniRule annotation2
Regioni185 – 186Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105F03 Bacteria
COG0796 LUCA
HOGENOMiHOG000262396
KOiK01776
OMAiVYGCTHY
OrthoDBiPOG091H00P1

Family and domain databases

HAMAPiMF_00258 Glu_racemase, 1 hit
InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR033134 Asp/Glu_racemase_AS_2
IPR004391 Glu_race
PANTHERiPTHR21198:SF2 PTHR21198:SF2, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00067 glut_race, 1 hit
PROSITEiView protein in PROSITE
PS00924 ASP_GLU_RACEMASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1I4X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKGTVGLFD SGVGGLTVVR EVSVILPGKR VIYFGDTAHV PYGDKSVDEL
60 70 80 90 100
LSYAERIIGF LCSQGADYII FACNTSSAVS LRLMRDRFQV PMIGLIEPGA
110 120 130 140 150
AEAVRLSATG RIGLIATEAT VKAGAYARAV SALNRNCQVF SQAAPRLVPL
160 170 180 190 200
VESGESDTPK AEQAVREYLE PLREQGIDTL ILGCTHYPFL RDVIERVLGP
210 220 230 240 250
EVVLVDPAAA TVRAARLDML RRGFSADNPG AQGEQDTVSL RYFVSGSADA
260 270
FRAVAGQFLG REPEPVTEIC LLR
Length:273
Mass (Da):29,306
Last modified:April 29, 2008 - v1
Checksum:i72341ADBECC5091F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000860 Genomic DNA Translation: ACA60014.1
RefSeqiWP_012302596.1, NC_010424.1

Genome annotation databases

EnsemblBacteriaiACA60014; ACA60014; Daud_1508
KEGGidau:Daud_1508

Similar proteinsi

Entry informationi

Entry nameiMURI_DESAP
AccessioniPrimary (citable) accession number: B1I4X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health