B1HY49 (B1HY49_LYSSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
Short name=Holo-ACP synthase HAMAP MF_00101
EC=2.7.8.7 HAMAP MF_00101

Alternative name(s):
4'-phosphopantetheinyl transferase AcpS HAMAP MF_00101

Gene names

Name:	acpS HAMAP MF_00101
Ordered Locus Names:	Bsph_4305

Organism

Lysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP] EMBL ACA41764.1

Taxonomic identifier

444177 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101
Catalytic activity	CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101
Cofactor	Magnesium By similarity. HAMAP MF_00101
Subcellular location	Cytoplasm By similarity HAMAP MF_00101.
Sequence similarities	Belongs to the P-Pant transferase superfamily. AcpS family. HAMAP MF_00101

Ontologies

Keywords
Biological process	Fatty acid biosynthesis HAMAP MF_00101 Lipid synthesis
Cellular component	Cytoplasm HAMAP MF_00101
Ligand	Magnesium HAMAP MF_00101 Metal-binding HAMAP MF_00101
Molecular function	Transferase HAMAP MF_00101 EMBL ACA41764.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP macromolecule biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	holo-[acyl-carrier-protein] synthase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	30	1	Magnesium By similarity HAMAP MF_00101
	Metal binding	80	1	Magnesium By similarity HAMAP MF_00101

Sequences

	Sequence		Length	Mass (Da)
	B1HY49 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 85F5BEFF58AA3D7D	FASTA	139	15,607
	10 20 30 40 50 60 MAPPQFTIII HALLEIGKGE GHMIKGIGLD IVEIDRIEKA MKRTDKFKDR ILTTREKILF 70 80 90 100 110 120 DSYSETRKVE FLAGRFAAKE AFSKAMGTGI GEQCKLHDME ILRGKAGNPV LYFKEELAHG 130 FVSITHSKQY AAAQVILLE

References

[1]

"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species." Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z. J. Bacteriol. 190:2892-2902(2008) [PubMed: 18296527] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000817 Genomic DNA. Translation: ACA41764.1.
RefSeq	YP_001699894.1. NC_010382.1.
3D structure databases
ProteinModelPortal	B1HY49.
ModBase	Search...
Protein-protein interaction databases
STRING	B1HY49.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6022584.
GenomeReviews	Gene locus Bsph_4305 in contig CP000817_GR.
KEGG	lsp:Bsph_4305.
PATRIC	22421117. VBILysSph89750_4385.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734479.
OMA	VHVSITH.
Family and domain databases
HAMAP	MF_00101. AcpS. [Tree]
InterPro	IPR008278. 4-PPantetheinyl_Trfase. IPR002582. ACPS. IPR004568. PPantethiene-prot_Trfase. [Graphical view]
Gene3D	G3DSA:3.90.470.20. G3DSA:3.90.470.20. 1 hit.
KO	K00997.
Pfam	PF01648. ACPS. 1 hit. [Graphical view]
ProDom	PD004282. PPantethiene-prot_Trfase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF56214. 4-PPT_transf. 1 hit.
TIGRFAMs	TIGR00516. AcpS. 1 hit. TIGR00556. Pantethn_trn. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1HY49_LYSSC

Accession

Primary (citable) accession number: B1HY49

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)