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B1HY46 (B1HY46_LYSSC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201

EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr HAMAP MF_01201
Ordered Locus Names:Bsph_4302
OrganismLysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP] EMBL ACA41761.1
Taxonomic identifier444177 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeLysinibacillus

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site571Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2851Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue571N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
B1HY46 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 316269A65711E745

FASTA38942,923
        10         20         30         40         50         60 
MYVIHNVLIK NKEGILMKTQ QYFRPTKAMI DLQAIQQNIK NLKKFIRPNV QIIAVVKANA 

        70         80         90        100        110        120 
YGHGDVAVAQ AALEAGATIL AVATPDEALH IRAHFEEPDI LILGASPVSF APIAAQQRIM 

       130        140        150        160        170        180 
LTVYASEWVQ QAAPLLAKEA EPLQLHIKVD SGMGRIGIRS EQDLLALYQT IESIDNVELN 

       190        200        210        220        230        240 
GIFTHFATAD EKDTTYFDEQ VQFFESCLAV MPKKPLLVHA SNTAASLVKD SNLQYDAVRY 

       250        260        270        280        290        300 
GISMYGLSPS SYVESILPFA LQPAFSLESE LVHVKEIKKG ESVGYGATYV APSNMWIGTI 

       310        320        330        340        350        360 
PIGYADGVIR KLGGQEVLID GQRMPIVGRI CMDQCMVALP KAYAIGEKVT LIGQQGQNRI 

       370        380 
SIDEWATKLE TINYEIPCII TARVPRIYF 

« Hide

References

[1]"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
J. Bacteriol. 190:2892-2902(2008) [PubMed: 18296527] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000817 Genomic DNA. Translation: ACA41761.1.
RefSeqYP_001699891.1. NC_010382.1.

3D structure databases

ProteinModelPortalB1HY46.
SMRB1HY46. Positions 21-389.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1HY46.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6022926.
GenomeReviewsGene locus Bsph_4302 in contig CP000817_GR.
KEGGlsp:Bsph_4302.
PATRIC22421111. VBILysSph89750_4382.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG712172.
OMARTEEWIA.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1HY46_LYSSC
AccessionPrimary (citable) accession number: B1HY46
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)