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B1HX79 (B1HX79_LYSSC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine biosynthesis bifunctional protein ArgJ HAMAP MF_01106
Gene names
Name:argJ HAMAP MF_01106
Ordered Locus Names:Bsph_4194
OrganismLysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP] EMBL ACA41655.1
Taxonomic identifier444177 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length422 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate By similarity. HAMAP MF_01106

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01106

N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate. HAMAP MF_01106

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. HAMAP MF_01106

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01106

Subunit structure

Heterotetramer of two alpha and two beta chains By similarity. HAMAP MF_01106

Subcellular location

Cytoplasm By similarity HAMAP MF_01106.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway By similarity. HAMAP MF_01106

Sequence similarities

Belongs to the ArgJ family. HAMAP MF_01106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site208 – 2092Cleavage; by autolysis By similarity HAMAP MF_01106

Sequences

Sequence LengthMass (Da)Tools
B1HX79 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 88197FCC3A767131

FASTA42244,894
        10         20         30         40         50         60 
MFSLMKNKEE LWMTVTTSIN VMKKLSSKNI VSPKGFKAAG LHCGLKHKKK DLAILVSEVP 

        70         80         90        100        110        120 
ASVAGVFTTN AVQAAPLKVT KEVVYTTKKM QAIIVNSGNA NACTGKQGVK DAQTMQAQVA 

       130        140        150        160        170        180 
EKLGIAPELV GVCSTGVIGE MMKLEPVVNG IQQLEPKDNL ESAIDFAQAI LTTDTVMKNT 

       190        200        210        220        230        240 
SYSTTVDGKE IIIAGVAKGS GMIEPNMATM LGFITTDAQI ESDVLQSALS DITNLTFNAI 

       250        260        270        280        290        300 
TVDGDTSTND TVVVLANGFA GNKTLTPDHP DWLNFYYTLK TVAEDLAKMI AKDGEGATKL 

       310        320        330        340        350        360 
IEVEVVGAVA DEEARKIAKS VVGSPLVKTA VFGCDANWGR IIAAVGYSGA TVDPDKITIQ 

       370        380        390        400        410        420 
IGGATMVENG EPIPFSEDEL IQILKMHEVK IYVSLGMGEG KGHAWGCDLT YDYVQINASY 


RS

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References

[1]"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
J. Bacteriol. 190:2892-2902(2008) [PubMed: 18296527] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000817 Genomic DNA. Translation: ACA41655.1.
RefSeqYP_001699785.1. NC_010382.1.

3D structure databases

ProteinModelPortalB1HX79.
SMRB1HX79. Positions 20-420.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1HX79.

Protein family/group databases

MEROPST05.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6022873.
GenomeReviewsGene locus Bsph_4194 in contig CP000817_GR.
KEGGlsp:Bsph_4194.
PATRIC22420829. VBILysSph89750_4271.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284202.
OMAFPKLATR.

Family and domain databases

HAMAPMF_01106. ArgJ.
[Tree]
InterProIPR002813. Arg_biosynth_ArgJ.
IPR016117. Pept_S58_DmpA/Arg_biosyn_ArgJ.
[Graphical view]
KOK00620.
PANTHERPTHR23100. ArgJ. 1 hit.
PfamPF01960. ArgJ. 1 hit.
[Graphical view]
ProDomPD004193. Arg_biosynth_ArgJ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56266. Pept_S58_DmpA/Arg_biosyn_ArgJ. 1 hit.
TIGRFAMsTIGR00120. ArgJ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1HX79_LYSSC
AccessionPrimary (citable) accession number: B1HX79
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info