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B1HX11 (B1HX11_LYSSC) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Bsph_4121 EMBL ACA41587.1
OrganismLysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP] EMBL ACA41587.1
Taxonomic identifier444177 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeLysinibacillus

Protein attributes

Sequence length429 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
B1HX11 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 6EBA6A1B4CA1BBE7

FASTA42947,020
        10         20         30         40         50         60 
MIMNLGGNRM SNKIVVENGV LNVPNNPVIP FIEGDGIGPD IWAAASRVID AAVEKAYNGE 

        70         80         90        100        110        120 
KKIEWLEVLA GEKAFNQTGE WLPQETLDKI NEYLIAIKGP LTTPIGGGIR SLNVALRQQL 

       130        140        150        160        170        180 
DLYVCLRPVR HFDGVPSPVK RPEDVDMVIF RENTEDIYAG IEFESGSEQA QKIINFLQSE 

       190        200        210        220        230        240 
FGVNQIRFPE TSGIGVKPVS KEGTERLVRS AIEYAIKHKR PSVTLVHKGN IMKFTEGGFK 

       250        260        270        280        290        300 
KWGYELAEKE FADQTFTWNQ YDAIKAEQGE EAANKAQSDA LAAGKILVKD SIADIFLQQI 

       310        320        330        340        350        360 
LTRPTEFDVV ATMNLNGDYI SDALAAQVGG IGIAPGANIN YVTGHAIFEA THGTAPKYAG 

       370        380        390        400        410        420 
LDKVNPSSVL LSGVLMLEHL GWQEAADMIT KSVEQTISSK VVTYDFARLM DGATEVKCSE 


FANELIKNL 

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References

[1]"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
J. Bacteriol. 190:2892-2902(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C3-41.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000817 Genomic DNA. Translation: ACA41587.1.
RefSeqYP_001699717.1. NC_010382.1.

3D structure databases

ProteinModelPortalB1HX11.
SMRB1HX11. Positions 13-429.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING444177.Bsph_4121.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACA41587; ACA41587; Bsph_4121.
GeneID6022806.
KEGGlsp:Bsph_4121.
PATRIC22420685. VBILysSph89750_4199.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
OrthoDBEOG6SNDTP.
ProtClustDBPRK07006.

Enzyme and pathway databases

BioCycLSPH444177:GJEL-4094-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1HX11_LYSSC
AccessionPrimary (citable) accession number: B1HX11
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: November 13, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)