Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B1HTV6

- PUR5_LYSSC

UniProt

B1HTV6 - PUR5_LYSSC

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Lysinibacillus sphaericus (strain C3-41)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciLSPH444177:GJEL-230-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:Bsph_0216
    OrganismiLysinibacillus sphaericus (strain C3-41)
    Taxonomic identifieri444177 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeLysinibacillus
    ProteomesiUP000002164: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 351351Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000193031Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi444177.Bsph_0216.

    Structurei

    3D structure databases

    ProteinModelPortaliB1HTV6.
    SMRiB1HTV6. Positions 13-343.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OMAiEFEMYRT.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B1HTV6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKAYEQAGV NIEAGYEAVK RMKSHVERTN RLGVMGTFGG FGGMFDLSEL    50
    NLKEPVLISG TDGVGTKLKL AFMVDKHDTI GVDCVAMCVN DIVAQGAEPL 100
    YFLDYVALGK AEPAKIEQIV KGVADGCVQS GAALIGGETA EMPGLYEEDE 150
    YDLAGFAVGA CEKSAIVTGE RIVEGDVLIG IASSGVHSNG YSLVRKIVFA 200
    DRQYAVDAIV ENYEDLGPIG EALLVPTKLY AKPVLAALKA ADVHGCAHVT 250
    GGGFYENLPR MMPEGLATEI DLGSWPVLRI FEFLKDKGQL EDKDLYNVFN 300
    MGIGFVIAAP AAEADKVMAA VEANGEKAYT IGRVIKGNGV VFNGTHDGSL 350
    V 351
    Length:351
    Mass (Da):37,181
    Last modified:April 29, 2008 - v1
    Checksum:i9083A79BF3DF6AF3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000817 Genomic DNA. Translation: ACA37847.1.
    RefSeqiWP_012292016.1. NC_010382.1.
    YP_001695977.1. NC_010382.1.

    Genome annotation databases

    EnsemblBacteriaiACA37847; ACA37847; Bsph_0216.
    GeneIDi6021864.
    KEGGilsp:Bsph_0216.
    PATRICi22412888. VBILysSph89750_0363.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000817 Genomic DNA. Translation: ACA37847.1 .
    RefSeqi WP_012292016.1. NC_010382.1.
    YP_001695977.1. NC_010382.1.

    3D structure databases

    ProteinModelPortali B1HTV6.
    SMRi B1HTV6. Positions 13-343.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 444177.Bsph_0216.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACA37847 ; ACA37847 ; Bsph_0216 .
    GeneIDi 6021864.
    KEGGi lsp:Bsph_0216.
    PATRICi 22412888. VBILysSph89750_0363.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OMAi EFEMYRT.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci LSPH444177:GJEL-230-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
      Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
      J. Bacteriol. 190:2892-2902(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C3-41.

    Entry informationi

    Entry nameiPUR5_LYSSC
    AccessioniPrimary (citable) accession number: B1HTV6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3