ID   B1HSZ6_LYSSC            Unreviewed;       500 AA.
AC   B1HSZ6;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:ACA37750.1};
DE            EC=1.2.1.3 {ECO:0000313|EMBL:ACA37750.1};
GN   OrderedLocusNames=Bsph_0114 {ECO:0000313|EMBL:ACA37750.1};
OS   Lysinibacillus sphaericus (strain C3-41).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX   NCBI_TaxID=444177 {ECO:0000313|EMBL:ACA37750.1, ECO:0000313|Proteomes:UP000002164};
RN   [1] {ECO:0000313|EMBL:ACA37750.1, ECO:0000313|Proteomes:UP000002164}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C3-41 {ECO:0000313|EMBL:ACA37750.1,
RC   ECO:0000313|Proteomes:UP000002164};
RX   PubMed=18296527; DOI=10.1128/JB.01652-07;
RA   Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M.,
RA   Berry C., Yuan Z.;
RT   "Complete genome sequence of the mosquitocidal bacterium Bacillus
RT   sphaericus C3-41 and comparison with those of closely related Bacillus
RT   species.";
RL   J. Bacteriol. 190:2892-2902(2008).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000817; ACA37750.1; -; Genomic_DNA.
DR   AlphaFoldDB; B1HSZ6; -.
DR   EnsemblBacteria; ACA37750; ACA37750; Bsph_0114.
DR   KEGG; lsp:Bsph_0114; -.
DR   HOGENOM; CLU_005391_0_1_9; -.
DR   Proteomes; UP000002164; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          34..494
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        270
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   500 AA;  54309 MW;  C6B6A7B1A0684385 CRC64;
     MEKGGRLMEA VLTLKPQIKE FLQSTIGLYI DGKYVQAQSG KTLNVLNPAN EEVIAVVSEA
     QAEDIDLAVH AAQQAFEGQW SMMEAAERSR IIYKLADLLE EHREELAQLE SLDNGKPYKA
     ALADDVDGTV QHFRYYAGWA TKITGQTVQV SKDYLNYIVH EPVGVVGQII PWNFPLAMAA
     WKLGAALAVG CTVVIKPAAE TPLSLLYVGQ LMKQAGFPDG VVNIVPGTGE AGEAIVTHKG
     VAKVAFTGST KTGIHVMKKA ADDVKSITLE LGGKSPAIVL PDADVEEAIE GTFAGTMYNH
     GQNCSACTRV FVHSSLYNLF IERLAEKAKA LKIGSGLDPE TDMGPLVSQK QLNTVLDYIE
     KGKEEGARIV AGGDRALEKG YFVQPTIFAD VQDTMIIAQE EIFGPVMSIL SFETVDEVIV
     RANNSKYGLA ASIWTENVKK AHYIASKLQA GTVWINDFGL EWETMPFGGY KQSGIGREMG
     GEYGLSNYTE VKSVFVNMKQ
//