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Protein

Adenine deaminase

Gene

ade

Organism
Lysinibacillus sphaericus (strain C3-41)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciLSPH444177:GJEL-3343-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Bsph_3357
OrganismiLysinibacillus sphaericus (strain C3-41)
Taxonomic identifieri444177 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeLysinibacillus
Proteomesi
  • UP000002164 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 581581Adenine deaminasePRO_1000146243Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi444177.Bsph_3357.

Structurei

3D structure databases

ProteinModelPortaliB1HR71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

B1HR71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTKLQQLTQ NILSSQGKLE ADFILKNAQV ADVYTLTWRK ADIVVKNGTI
60 70 80 90 100
VALDHSNRFH AKEVEDAAGS YVIPGLIDGH IHIESSMLTP GEFSRVLIPH
110 120 130 140 150
GITTVITDPH EIANVAGAEG IQFMLDDAQK ADMDIFVMLP SSVPGTQFEN
160 170 180 190 200
AGATLTAQDL EPFLHHEQVR GLAEVMDFPA VLNGEEGMLQ KILLSKEANL
210 220 230 240 250
VIDGHCAGLQ SEQITGYRAA GIQTDHECVT AEEAIDRVEQ GMYVLIREGS
260 270 280 290 300
AAKNLRDLLP AIQSHNARRF GFCTDDKYVD ELMDEGSINY DVAMAIAEGM
310 320 330 340 350
TPLQAIQLAT VNTAECYRLF DRGVLAPGYK ADFVLVDDLS TMQAKAVWKN
360 370 380 390 400
GHKVAENGEM LTSRQEAKVP AHIHHSVHLP SMTKDSLQLS FKKGTRANVM
410 420 430 440 450
EIVPNQLITN HLVIDVPVKE GVFVPSIEQD LLKLAVIERH HHLHTTGLGI
460 470 480 490 500
VKGFGLQKGA VATTVAHDSH NALVVGTNDE DMILALSRIQ EIQGGFVIVA
510 520 530 540 550
DGEILAEMPL TIGGLMTDVP AQQAKEQLAG LHNALQKLNP TLDFHFLLTF
560 570 580
SFVALPVIPA LKLTDTGLFD VTTFQHIEVE A
Length:581
Mass (Da):63,343
Last modified:April 29, 2008 - v1
Checksum:i6D93DF4A6EF4FDDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000817 Genomic DNA. Translation: ACA40851.1.

Genome annotation databases

EnsemblBacteriaiACA40851; ACA40851; Bsph_3357.
KEGGilsp:Bsph_3357.
PATRICi22419161. VBILysSph89750_3438.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000817 Genomic DNA. Translation: ACA40851.1.

3D structure databases

ProteinModelPortaliB1HR71.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444177.Bsph_3357.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA40851; ACA40851; Bsph_3357.
KEGGilsp:Bsph_3357.
PATRICi22419161. VBILysSph89750_3438.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciLSPH444177:GJEL-3343-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
    Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
    J. Bacteriol. 190:2892-2902(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C3-41.

Entry informationi

Entry nameiADEC_LYSSC
AccessioniPrimary (citable) accession number: B1HR71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: June 8, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.