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B1HPF7 (B1HPF7_LYSSC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:Bsph_3090
OrganismLysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP] EMBL ACA40603.1
Taxonomic identifier444177 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818

Subcellular location

Cytoplasm By similarity HAMAP MF_00818.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
B1HPF7 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 6311757BEC4512BB

FASTA17720,584
        10         20         30         40         50         60 
MLGNILQGGF FMSGRSHEEG LKDLTLLGNQ GTNYSFEYAP EVLEAVDNLH SNRDYFVKFN 

        70         80         90        100        110        120 
CPEFTSLCPL TNQPDFATMY ISYIPDKKIV ESKSLKLYLF SFRNHGDFHE DCVNIIMNDL 

       130        140        150        160        170 
ITLLDPRYIE VWGKFTPRGG ISIDPWCNYG KPETKYEEIA NYRLMNHDLY PEKIDNR

« Hide

References

[1]"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
J. Bacteriol. 190:2892-2902(2008) [PubMed: 18296527] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000817 Genomic DNA. Translation: ACA40603.1.
RefSeqYP_001698733.1. NC_010382.1.

3D structure databases

ProteinModelPortalB1HPF7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1HPF7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6024873.
GenomeReviewsGene locus Bsph_3090 in contig CP000817_GR.
KEGGlsp:Bsph_3090.
PATRIC22418634. VBILysSph89750_3175.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294103.
OMAFATLYIN.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1HPF7_LYSSC
AccessionPrimary (citable) accession number: B1HPF7
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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