B1HNU2 (MQO_LYSSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	Bsph_4711

Organism

Lysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP]

Taxonomic identifier

444177 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 493	493	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000099875

Sequences

	Sequence		Length	Mass (Da)
	B1HNU2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: ED14F52062307477	FASTA	493	54,324
	10 20 30 40 50 60 MSNRQIKSDV ILIGAGIMSA TLGTILKELA PDWKITVFEK LEKAGEESSH ELNNAGTGHA 70 80 90 100 110 120 ALCELNYTSE KKDGSIDIKK AINVNEQFQV SRQFWSYLVN NKLINNPQDF IMPLPHMSLV 130 140 150 160 170 180 QGKENVEFLK KRHETMIQNP LFEGMEFSND PETLKKWIPL IMENRPAGED IAATKIDTGT 190 200 210 220 230 240 DVNFGALTRM LIDHLKAKDV DVNYNHSVES LKQASDGSWE VRVHDLDGCK MEYHSAKFVF 250 260 270 280 290 300 LGAGGGSLEL LQKSGIPEGK HIGGFPISGL FLACNNPEVA EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRYIDN KKSLLFGPFA GFSPKFLKTG SNMDLFASVK PHNITTLLAA GVKEMGLTKY 370 380 390 400 410 420 LIQQLMLSKE QRMEELREFI PNAKSDDWDI IVAGQRVQVI KDTEAGGKGT LQFGTEVVSA 430 440 450 460 470 480 ADGSIAALLG ASPGASTAVH VMLEVINKCF PQHIKEWEAK IKEMIPSYGL SLAENPELLK 490 EINATTDEAL RLK

References

[1]

"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species." Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z. J. Bacteriol. 190:2892-2902(2008) [PubMed: 18296527] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C3-41.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000817 Genomic DNA. Translation: ACA42155.1.
RefSeq	YP_001700285.1. NC_010382.1.
3D structure databases
ProteinModelPortal	B1HNU2.
ModBase	Search...
Protein-protein interaction databases
STRING	B1HNU2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6022936.
GenomeReviews	Gene locus Bsph_4711 in contig CP000817_GR.
KEGG	lsp:Bsph_4711.
PATRIC	22421939. VBILysSph89750_4787.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	KKWVPLM.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	LSPH444177:BSPH_4711-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_LYSSC

Accession

Primary (citable) accession number: B1HNU2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program