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B1HNE2 (B1HNE2_LYSSC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha 1 HAMAP MF_00823
Short name=ACCase subunit alpha 1 HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha 1 HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA1 HAMAP MF_00823
Ordered Locus Names:Bsph_2923
OrganismLysinibacillus sphaericus (strain C3-41) [Complete proteome] [HAMAP] EMBL ACA40452.1
Taxonomic identifier444177 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Lysinibacillus

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823

Subcellular location

Cytoplasm By similarity HAMAP MF_00823.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
B1HNE2 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: EF7BD35B68A72D28

FASTA31835,293
        10         20         30         40         50         60 
MSKNFAFEEP VVQLREKIDE LKTIATEANV DMTGEIERLE TRLTQLEQSI YANMKPWDRV 

        70         80         90        100        110        120 
QVARHPERPT TLQYIEAMCE NFIELHGDRK FGDDAAILGG IALFEGQPVT IVGHQRGKST 

       130        140        150        160        170        180 
KENIRRNFGM PHPEGYRKAL RLMKQAEKFK RPIICFIDTK GAYPGKAAEE RGPSEAIART 

       190        200        210        220        230        240 
LSEMAILTVP VISIVIGEGG SGGAIALGVA NRVFMLENST YSVISPEGAA SILWRDGSLG 

       250        260        270        280        290        300 
KQAAEAMRIT APDLKELDVI DGIIPEITGG AHRNVVKQAF YIKECISVTL KALNSLNGEQ 

       310 
LIEDRYEKFR KIGQYTEA

« Hide

References

[1]"Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species."
Hu X., Fan W., Han B., Liu H., Zheng D., Li Q., Dong W., Yan J., Gao M., Berry C., Yuan Z.
J. Bacteriol. 190:2892-2902(2008) [PubMed: 18296527] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000817 Genomic DNA. Translation: ACA40452.1.
RefSeqYP_001698582.1. NC_010382.1.

3D structure databases

ProteinModelPortalB1HNE2.
SMRB1HNE2. Positions 5-317.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1HNE2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6024126.
GenomeReviewsGene locus Bsph_2923 in contig CP000817_GR.
KEGGlsp:Bsph_2923.
PATRIC22418308. VBILysSph89750_3013.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG286557.
OMATIATEAN.
ProtClustDBCLSK2333652.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1HNE2_LYSSC
AccessionPrimary (citable) accession number: B1HNE2
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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