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B1HAX4 (B1HAX4_BURPS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL EDS84366.1
ORF Names:BURPSS13_A0096 EMBL EDS84366.1
OrganismBurkholderia pseudomallei S13 EMBL EDS84366.1
Taxonomic identifier320374 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2261Iron By similarity HAMAP MF_00323
Metal binding3071Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B1HAX4 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: CB37193FB9181959

FASTA36740,571
        10         20         30         40         50         60 
MSFDSVPRHA LSMRFDLEPP SHASAAHRVA VLLVNLGTPD APTPRAVRRY LAQFLSDPRV 

        70         80         90        100        110        120 
VEIPQLVWQV ILRTLILPLR GRASAKKYAA VWLPEGSPLR VYTERQVESV KPLFAANGYR 

       130        140        150        160        170        180 
VIVDYAMRYG TPSIADVLAQ LKRAGAERVL LLPMYPQYSS STTATAFDAA FAALGRMRNQ 

       190        200        210        220        230        240 
PEVRTVRHYA DHPAYIHALA EQVRQYWAAH GRPAFDAGDK LVLSFHGVPK RTLDLGDPYH 

       250        260        270        280        290        300 
DQCQQTAALL MSALGLTTFE CRVTFQSRFG KAEWLQPYTA PTLKELGAAG VRRADVFCPG 

       310        320        330        340        350        360 
FTADCLETIE EIGIEVRDEF VHGGGKEFHR IPCLNASPAW IAALGEIAAE NLQGWPVRVA 


MAPEAVS

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References

[1]"Annotation of Burkholderia pseudomallei S13."
DeShazer D., Woods D.E., Nierman W.C.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: S13 EMBL EDS84366.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH899765 Genomic DNA. Translation: EDS84366.1.

3D structure databases

ProteinModelPortalB1HAX4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC30416646. VBIBurPse99458_2485.

Phylogenomic databases

OMATIEEIGM.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1HAX4_BURPS
AccessionPrimary (citable) accession number: B1HAX4
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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