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Protein
Submitted name:

LOC100145511 protein

Gene

gad1.2

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. carboxy-lyase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. carboxylic acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
LOC100145511 proteinImported
Gene namesi
Name:gad1.2Imported
Synonyms:LOC100145511Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-5830282. gad1.2.

Expressioni

Gene expression databases

BgeeiB1H2Y8.
ExpressionAtlasiB1H2Y8. baseline.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000012900.

Structurei

3D structure databases

ProteinModelPortaliB1H2Y8.
SMRiB1H2Y8. Positions 41-540.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000005382.
HOVERGENiHBG004980.
KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1H2Y8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEKVGTCADE GNSQPKLLHE KHICQEKANE ERIMHSEKYI SDFSNIYSTD
60 70 80 90 100
LLPTRNGEKC TEQFLIEVLR ILLNHIKKTY DGESKVLDFH HPHQLLEGLE
110 120 130 140 150
GFNLELSDQP EPLEQILVDC SDTLKYSIKT GHPRYFNQLS CGLDIIGLAG
160 170 180 190 200
EWLTATANTN MFTYEIAPVF IIMEEIVLKK MQEIIGWGEN EADGIFSPGG
210 220 230 240 250
TISNLYSLQA ARYKYFPMVK TKGMAALPQI VIFTSEQSHY SFKKASAILG
260 270 280 290 300
IGTDNVIAIK CDERGKMIPS DLEDKILKAK RQGQHPFYVS ATAGTTVYGA
310 320 330 340 350
FDPLITIADI CKRYGLWMHV DAAWGGGLLL SKKHRYKMNG IERANSVTWN
360 370 380 390 400
PHKIMGVPLQ CSAILIRQKG LLQACNQQCA DYLFQMDKPY DTAYDTGDKT
410 420 430 440 450
IQCGRHVDIF KLWLMWKAKG SCGFELQINR CLELSEYLYN KLQSKSNFEL
460 470 480 490 500
VFRDKPEYTN VCFWYIPPSL EHVPRDKEWK ARLHKIAPQI KARMMEEGTV
510 520 530 540
MVSYQPQGDK PNFFRMVFSN PASKKSDVDF LLEEIERLGK GL
Length:542
Mass (Da):61,821
Last modified:April 29, 2008 - v1
Checksum:i3945B3426A7D4656
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161181 mRNA. Translation: AAI61181.1.
RefSeqiNP_001120426.1. NM_001126954.1.
UniGeneiStr.6300.

Genome annotation databases

GeneIDi100145511.
KEGGixtr:100145511.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC161181 mRNA. Translation: AAI61181.1.
RefSeqiNP_001120426.1. NM_001126954.1.
UniGeneiStr.6300.

3D structure databases

ProteinModelPortaliB1H2Y8.
SMRiB1H2Y8. Positions 41-540.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000012900.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100145511.
KEGGixtr:100145511.

Organism-specific databases

CTDi100137647.
XenbaseiXB-GENE-5830282. gad1.2.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000005382.
HOVERGENiHBG004980.
KOiK01580.

Gene expression databases

BgeeiB1H2Y8.
ExpressionAtlasiB1H2Y8. baseline.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: N6Imported.
    Tissue: OviductImported.

Entry informationi

Entry nameiB1H2Y8_XENTR
AccessioniPrimary (citable) accession number: B1H2Y8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 7, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.