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B1H292

- B1H292_RAT

UniProt

B1H292 - B1H292_RAT

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Protein
Submitted name:

Intramembrane protease 5

Gene

Sppl2c

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. aspartic-type endopeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseImported

Protein family/group databases

MEROPSiA22.004.

Names & Taxonomyi

Protein namesi
Submitted name:
Intramembrane protease 5Imported
Submitted name:
Protein Sppl2cImported
Submitted name:
Similar to intramembrane protease 5 (Predicted)Imported
Gene namesi
Name:Sppl2cImported
Synonyms:Imp5Imported, RGD1560562_predictedImported
ORF Names:rCG_35591Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 10

Organism-specific databases

RGDi1560562. Sppl2c.

Subcellular locationi

GO - Cellular componenti

  1. integral component of cytoplasmic side of endoplasmic reticulum membrane Source: Ensembl
  2. integral component of lumenal side of endoplasmic reticulum membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriB1H292.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000062920.
HOVERGENiHBG024193.
KOiK14212.
OMAiILWVAYR.
OrthoDBiEOG769ZJ4.

Family and domain databases

InterProiIPR007369. Peptidase_A22B_SPP.
IPR006639. Preselin/SPP.
IPR003137. Protease-assoc_domain.
[Graphical view]
PANTHERiPTHR12174. PTHR12174. 1 hit.
PfamiPF02225. PA. 1 hit.
PF04258. Peptidase_A22B. 1 hit.
[Graphical view]
SMARTiSM00730. PSN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1H292-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MACLGSLLPI GSLLLLLLSP EARGEYGVVR VVSKNWNKDY CVLYSSDYVT
60 70 80 90 100
LPRDLSHAPL LPLHDGTKTP WCPDEDSFHQ AQDSSLSQRP LHQTTTMVVR
110 120 130 140 150
GNCSFYAKGW LAQDHGAHGL LIVSRASNQQ CSDTTSKPQD PSKPRPALTI
160 170 180 190 200
PVAVLRYTDM LDILSHTYGD TNVHIAMYAP LEPIIDYNMV IIFILAVGTV
210 220 230 240 250
AAGGYWAGLM EADRLQRHQA RRGGGFGGHN QSQTVSAERS PRAWKEEDYE
260 270 280 290 300
DAAVDFTPAM TGAVVTMSCS IMVLLYFFYD CFVYIMIGIF GLGASTGLYS
310 320 330 340 350
CLAPIVRYLP LWQHQWVLPG HRASVKLSLL LLAGLCAMVT VLWVIYRNED
360 370 380 390 400
RWAWLLQDTL GVAYCLFVLR RVRLPTLKNC TSFLLALLAF DVFFVFITPL
410 420 430 440 450
FTKTGESIMV EVASGPVDSS SHERLPMVLK VPRMSFSALT LCDQPFSILG
460 470 480 490 500
FGDIVVPGFL VAYCHRFDVQ IQSRQVYYRA CTVAYAMGLL VTFVAMVLMQ
510 520 530 540 550
MGQPALLYLV SSTLLTSLVV ATCRQELTLF WTGQGRAKIP AEPVVQPCIV
560 570 580 590 600
SAVACRMKLE GVKDSRVTNR FEEAIDRESG DLDSNPGDDI AEMVTLSEDE
610 620 630 640 650
ATSPEGHSES SEGWSDTNLD PDELPSGSPM ALEELMPLAM LIPLIPPIPH
660 670 680 690
TSELGRIHTQ SRVRDSSLPW MGMHKRKGLK VKKSMSTQAP L
Length:691
Mass (Da):76,416
Last modified:April 29, 2008 - v1
Checksum:i58A733D854160FAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06065700 Genomic DNA. No translation available.
BC160911 mRNA. Translation: AAI60911.1.
CH473948 Genomic DNA. Translation: EDM06295.1.
RefSeqiNP_001099317.1. NM_001105847.1.
XP_006247566.1. XM_006247504.2.
UniGeneiRn.108313.

Genome annotation databases

EnsembliENSRNOT00000006808; ENSRNOP00000066080; ENSRNOG00000005104.
GeneIDi287753.
KEGGirno:287753.
UCSCiRGD:1560562. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06065700 Genomic DNA. No translation available.
BC160911 mRNA. Translation: AAI60911.1 .
CH473948 Genomic DNA. Translation: EDM06295.1 .
RefSeqi NP_001099317.1. NM_001105847.1.
XP_006247566.1. XM_006247504.2.
UniGenei Rn.108313.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi A22.004.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000006808 ; ENSRNOP00000066080 ; ENSRNOG00000005104 .
GeneIDi 287753.
KEGGi rno:287753.
UCSCi RGD:1560562. rat.

Organism-specific databases

CTDi 162540.
RGDi 1560562. Sppl2c.

Phylogenomic databases

GeneTreei ENSGT00530000062920.
HOVERGENi HBG024193.
KOi K14212.
OMAi ILWVAYR.
OrthoDBi EOG769ZJ4.

Miscellaneous databases

NextBioi 626958.

Gene expression databases

Genevestigatori B1H292.

Family and domain databases

InterProi IPR007369. Peptidase_A22B_SPP.
IPR006639. Preselin/SPP.
IPR003137. Protease-assoc_domain.
[Graphical view ]
PANTHERi PTHR12174. PTHR12174. 1 hit.
Pfami PF02225. PA. 1 hit.
PF04258. Peptidase_A22B. 1 hit.
[Graphical view ]
SMARTi SM00730. PSN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: TestisImported.
  2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. Ensembl
    Submitted (FEB-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiB1H292_RAT
AccessioniPrimary (citable) accession number: B1H292
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3