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B1GZW3

- TPIS_UNCTG

UniProt

B1GZW3 - TPIS_UNCTG

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Protein

Triosephosphate isomerase

Gene

tpiA

Organism
Uncultured termite group 1 bacterium phylotype Rs-D17
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate = glycerone phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei9 – 91SubstrateUniRule annotation
Binding sitei11 – 111SubstrateUniRule annotation
Active sitei95 – 951ElectrophileUniRule annotation
Active sitei167 – 1671Proton acceptorUniRule annotation

GO - Molecular functioni

  1. triose-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
  3. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis, Pentose shunt

Enzyme and pathway databases

BioCyciUTER471821:GJAD-338-MONOMER.
UniPathwayiUPA00109; UER00189.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Triosephosphate isomeraseUniRule annotation (EC:5.3.1.1UniRule annotation)
Short name:
TIMUniRule annotation
Alternative name(s):
Triose-phosphate isomeraseUniRule annotation
Gene namesi
Name:tpiAUniRule annotation
Ordered Locus Names:TGRD_312
OrganismiUncultured termite group 1 bacterium phylotype Rs-D17
Taxonomic identifieri471821 [NCBI]
Taxonomic lineageiBacteriaElusimicrobiaenvironmental samples
ProteomesiUP000001691: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 250250Triosephosphate isomerasePRO_1000096546Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi471821.TGRD_312.

Structurei

3D structure databases

ProteinModelPortaliB1GZW3.
SMRiB1GZW3. Positions 1-250.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the triosephosphate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0149.
HOGENOMiHOG000226412.
KOiK01803.
OMAiPAIYLDQ.
OrthoDBiEOG66QM23.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00147_B. TIM_B.
InterProiIPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
PANTHERiPTHR21139. PTHR21139. 1 hit.
PfamiPF00121. TIM. 1 hit.
[Graphical view]
SUPFAMiSSF51351. SSF51351. 1 hit.
TIGRFAMsiTIGR00419. tim. 1 hit.
PROSITEiPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1GZW3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKPLMAGNW KMNKTVSEAV SFVKALKGAV TGVSNVEILV CPAFTVLYEV
60 70 80 90 100
NNEIKGSNIN LGAQNLFGEA KGAFTGEIST AMIRDTGCSY VIVGHSERRQ
110 120 130 140 150
YFGETDEAVN KKTKAALAAD ITPIVCVGET LKERENNVTF SVIEKQVRNG
160 170 180 190 200
LADLTLQQAS LTVIAYEPVW AIGTGKTATP DQAQEVHSFI RKIYAQMYEE
210 220 230 240 250
SAEKVRILYG GSVNPGNVSD LMKKSDIDGG LVGGASLEAE SFTKLVKYSK
Length:250
Mass (Da):27,025
Last modified:April 29, 2008 - v1
Checksum:i5CFEDA283AAD4BB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009510 Genomic DNA. Translation: BAG13795.1.
RefSeqiWP_015423322.1. NC_020419.1.
YP_001956256.1. NC_020419.1.

Genome annotation databases

GeneIDi6372753.
KEGGirsd:TGRD_312.
PATRICi38570602. VBIUncTer52152_0496.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009510 Genomic DNA. Translation: BAG13795.1 .
RefSeqi WP_015423322.1. NC_020419.1.
YP_001956256.1. NC_020419.1.

3D structure databases

ProteinModelPortali B1GZW3.
SMRi B1GZW3. Positions 1-250.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471821.TGRD_312.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 6372753.
KEGGi rsd:TGRD_312.
PATRICi 38570602. VBIUncTer52152_0496.

Phylogenomic databases

eggNOGi COG0149.
HOGENOMi HOG000226412.
KOi K01803.
OMAi PAIYLDQ.
OrthoDBi EOG66QM23.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00189 .
UPA00138 .
BioCyci UTER471821:GJAD-338-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00147_B. TIM_B.
InterProi IPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view ]
PANTHERi PTHR21139. PTHR21139. 1 hit.
Pfami PF00121. TIM. 1 hit.
[Graphical view ]
SUPFAMi SSF51351. SSF51351. 1 hit.
TIGRFAMsi TIGR00419. tim. 1 hit.
PROSITEi PS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome of the uncultured termite group 1 bacteria in a single host protist cell."
    Hongoh Y., Sharma V.K., Prakash T., Noda S., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M.
    Proc. Natl. Acad. Sci. U.S.A. 105:5555-5560(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiTPIS_UNCTG
AccessioniPrimary (citable) accession number: B1GZW3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3