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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Uncultured termite group 1 bacterium phylotype Rs-D17
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:TGRD_010
OrganismiUncultured termite group 1 bacterium phylotype Rs-D17
Taxonomic identifieri471821 [NCBI]
Taxonomic lineageiBacteriaElusimicrobiaenvironmental samples
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000984571 – 312Methionyl-tRNA formyltransferaseAdd BLAST312

Proteomic databases

PRIDEiB1GZ11

Interactioni

Protein-protein interaction databases

STRINGi471821.TGRD_010

Structurei

3D structure databases

ProteinModelPortaliB1GZ11
SMRiB1GZ11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni107 – 110Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

B1GZ11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILFFGTAF ISETYLKELH KKCHEIFVVT TPDKPALRGQ KLIYPAVKVY
60 70 80 90 100
AVKNNISFIQ PEKFTLDVIE TIKNFAADTG VAVAYGKLIP KVVFDIPKYK
110 120 130 140 150
TFNIHFSLLP KYKGAAPVQH ALCRGETETG ISSFYIEEGL DTGGIIIQEK
160 170 180 190 200
LNISIKDNAE TLLNKLILLG IDVMNKTLEL FRCGKCDAAS QTGDPSFAPS
210 220 230 240 250
LKKIDGLVNW NKRAGEIYNQ FRGLYLWPGI YSTISQGKLV GKRIKFREIE
260 270 280 290 300
VFDSDSINKD SGIVYSAEKN RGFTVSCAVG RILVVKMQSE NKPVVSAWDF
310
IQGRQISAGD RF
Length:312
Mass (Da):34,892
Last modified:April 29, 2008 - v1
Checksum:i9387E512CCBA33F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009510 Genomic DNA Translation: BAG13493.1
RefSeqiYP_001955954.1, NC_020419.1

Genome annotation databases

EnsemblBacteriaiBAG13493; BAG13493; TGRD_010
KEGGirsd:TGRD_010
PATRICifig|471821.5.peg.20

Entry informationi

Entry nameiFMT_UNCTG
AccessioniPrimary (citable) accession number: B1GZ11
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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