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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Uncultured termite group 1 bacterium phylotype Rs-D17
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciUTER471821:GJAD-11-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:TGRD_010
OrganismiUncultured termite group 1 bacterium phylotype Rs-D17
Taxonomic identifieri471821 [NCBI]
Taxonomic lineageiBacteriaElusimicrobiaenvironmental samples
Proteomesi
  • UP000001691 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 312312Methionyl-tRNA formyltransferasePRO_1000098457Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi471821.TGRD_010.

Structurei

3D structure databases

ProteinModelPortaliB1GZ11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni107 – 1104Tetrahydrofolate (THF) bindingUniRule annotation

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE. Bacteria.
COG0223. LUCA.
HOGENOMiHOG000261177.
KOiK00604.
OMAiNCITTFR.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPiMF_00182. Formyl_trans. 1 hit.
InterProiIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
[Graphical view]
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsiTIGR00460. fmt. 1 hit.

Sequencei

Sequence statusi: Complete.

B1GZ11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILFFGTAF ISETYLKELH KKCHEIFVVT TPDKPALRGQ KLIYPAVKVY
60 70 80 90 100
AVKNNISFIQ PEKFTLDVIE TIKNFAADTG VAVAYGKLIP KVVFDIPKYK
110 120 130 140 150
TFNIHFSLLP KYKGAAPVQH ALCRGETETG ISSFYIEEGL DTGGIIIQEK
160 170 180 190 200
LNISIKDNAE TLLNKLILLG IDVMNKTLEL FRCGKCDAAS QTGDPSFAPS
210 220 230 240 250
LKKIDGLVNW NKRAGEIYNQ FRGLYLWPGI YSTISQGKLV GKRIKFREIE
260 270 280 290 300
VFDSDSINKD SGIVYSAEKN RGFTVSCAVG RILVVKMQSE NKPVVSAWDF
310
IQGRQISAGD RF
Length:312
Mass (Da):34,892
Last modified:April 29, 2008 - v1
Checksum:i9387E512CCBA33F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009510 Genomic DNA. Translation: BAG13493.1.
RefSeqiWP_015423022.1. NC_020419.1.
YP_001955954.1. NC_020419.1.

Genome annotation databases

EnsemblBacteriaiBAG13493; BAG13493; TGRD_010.
KEGGirsd:TGRD_010.
PATRICi38569600. VBIUncTer52152_0020.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009510 Genomic DNA. Translation: BAG13493.1.
RefSeqiWP_015423022.1. NC_020419.1.
YP_001955954.1. NC_020419.1.

3D structure databases

ProteinModelPortaliB1GZ11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi471821.TGRD_010.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG13493; BAG13493; TGRD_010.
KEGGirsd:TGRD_010.
PATRICi38569600. VBIUncTer52152_0020.

Phylogenomic databases

eggNOGiENOG4105CAE. Bacteria.
COG0223. LUCA.
HOGENOMiHOG000261177.
KOiK00604.
OMAiNCITTFR.

Enzyme and pathway databases

BioCyciUTER471821:GJAD-11-MONOMER.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPiMF_00182. Formyl_trans. 1 hit.
InterProiIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
[Graphical view]
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsiTIGR00460. fmt. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFMT_UNCTG
AccessioniPrimary (citable) accession number: B1GZ11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.