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Protein

Non-specific serine/threonine protein kinase

Gene

Pak3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:Pak3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339656 Pak3

PTM / Processingi

Proteomic databases

MaxQBiB1GX80
PeptideAtlasiB1GX80
PRIDEiB1GX80

Expressioni

Gene expression databases

GenevisibleiB1GX80 MM

Structurei

3D structure databases

ProteinModelPortaliB1GX80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 83CRIBInterPro annotationAdd BLAST14
Domaini289 – 540Protein kinaseInterPro annotationAdd BLAST252

Phylogenomic databases

eggNOGiKOG0578 Eukaryota
ENOG410XP4K LUCA
HOVERGENiHBG108518

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
cd06656 STKc_PAK3, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR035065 PAK2/3
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR035063 STK_PAK3
PANTHERiPTHR24361:SF250 PTHR24361:SF250, 1 hit
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

B1GX80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS
60 70 80 90 100
IFPGGGDKTN KKKEKERPEI SLPSDFEHTI HVGFDAVTGE FTNSPFQTSR
110 120 130 140 150
PVTVASSQSE GKMGIPEQWA RLLQTSNITK LEQKKNPQAV LDVLKFYDSK
160 170 180 190 200
ETVNNQKYMS FTSGDKSAHG YIAAHQSNTK TASEPPLAPP VSEEEDEEEE
210 220 230 240 250
EEEDDNEPPP VIAPRPEHTK SIYTRSVVES IASPAAPNKE DIPPSAENAN
260 270 280 290 300
STTLYRNTDR QRKKSKMTDE EILEKLRSIV SVGDPKKKYT RFEKIGQGAS
310 320 330 340 350
GTVYTALDIA TGQEVAIKQM NLQQQPKKEL IINEILVMRE NKNPNIVNYL
360 370 380 390 400
DSYLVGDELW VVMEYLAGGS LTDVVTETCM DEGQIAAVCR ECLQALDFLH
410 420 430 440 450
SNQVIHRDIK SDNILLGMDG SVKLTDFGFC AQITPEQSKR STMVGTPYWM
460 470 480 490 500
APEVVTRKAY GPKVDIWSLG IMAIEMVEGE PPYLNENPLR ALYLIATNGT
510 520 530 540 550
PELQNPERLS AVFRDFLNRC LEMDVDRRGS AKELLQHPFL KLAKPLSSLT
560
PLIIAAKEAI KNSSR
Length:565
Mass (Da):63,001
Last modified:April 29, 2008 - v1
Checksum:i922103D765B50B90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM943853 mRNA Translation: CAQ16019.1
RefSeqiNP_001181976.1, NM_001195047.1
UniGeneiMm.40035

Genome annotation databases

GeneIDi18481
UCSCiuc012hpu.1 mouse

Similar proteinsi

Entry informationi

Entry nameiB1GX80_MOUSE
AccessioniPrimary (citable) accession number: B1GX80
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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