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Protein
Submitted name:

Cinnamate-4-hydroxylase

Gene

C4H

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. monooxygenase activity Source: UniProtKB-KW
  4. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cinnamate-4-hydroxylaseImported
Gene namesi
Name:C4HImported
Ordered Locus Names:At2g30490Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Organism-specific databases

TAIRiAT2G30490.

PTM / Processingi

Proteomic databases

PRIDEiB1GV49.

Expressioni

Gene expression databases

ExpressionAtlasiB1GV49. baseline and differential.
GenevestigatoriB1GV49.

Structurei

3D structure databases

ProteinModelPortaliB1GV49.
SMRiB1GV49. Positions 30-484.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

KOiK00487.
OMAiGITIGRM.
PhylomeDBiB1GV49.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1GV49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLLLLEKSL IAVFVAVILA TVISKLRGKK LKLPPGPIPI PIFGNWLQVG
60 70 80 90 100
DDLNHRNLVD YAKKFGDLFL LRMGQRNLVV VSSPDLTKEV LLTQGVEFGS
110 120 130 140 150
RTRNVVFDIF TGKGQDMVFT VYGEHWRKMR RIMTVPFFTN KVVQQNREGW
160 170 180 190 200
EFEAASVVED VKKNPDSATK GIVLRKRLQL MMYNNMFRIM FDRRFESEDD
210 220 230 240 250
PLFLRLKALN GERSRLAQSF EYNYGDFIPI LRPFLRGYLK ICQDVKDRRI
260 270 280 290 300
ALFKKYFVDE RKQIASSKPT GSEGLKCAID HILEAEQKGE INEDNVLYIV
310 320 330 340 350
ENINVAAIET TLWSIEWGIA ELVNHPEIQS KLRNELDTVL GPGVQVTEPD
360 370 380 390 400
LHKLPYLQAV VKETLRLRMA IPLLVPHMNL HDAKLAGYDI PAESKILVNA
410 420 430 440 450
WWLANNPNSW KKPEEFRPER FFEEESHVEA NGNDFRYVPF GVGRRSCPGI
460 470 480 490 500
ILALPILGIT IGRMVQNFEL LPPPGQSKVD TSEKGGQFSL HILNHSIIVM

KPRNC
Length:505
Mass (Da):57,792
Last modified:April 29, 2008 - v1
Checksum:i61DEAAA9463362CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM887631 Genomic DNA. Translation: CAP08840.1.
AM887632 Genomic DNA. Translation: CAP08841.1.
RefSeqiNP_180607.1. NM_128601.2.
UniGeneiAt.23450.

Genome annotation databases

GeneIDi817599.
KEGGiath:AT2G30490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM887631 Genomic DNA. Translation: CAP08840.1.
AM887632 Genomic DNA. Translation: CAP08841.1.
RefSeqiNP_180607.1. NM_128601.2.
UniGeneiAt.23450.

3D structure databases

ProteinModelPortaliB1GV49.
SMRiB1GV49. Positions 30-484.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB1GV49.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi817599.
KEGGiath:AT2G30490.

Organism-specific databases

TAIRiAT2G30490.

Phylogenomic databases

KOiK00487.
OMAiGITIGRM.
PhylomeDBiB1GV49.

Gene expression databases

ExpressionAtlasiB1GV49. baseline and differential.
GenevestigatoriB1GV49.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Multilocus analysis of variation using a large empirical data set: phenylpropanoid pathway genes in Arabidopsis thaliana."
    Ramos-Onsins S.E., Puerma E., Balana-Alcaide D., Salguero D., Aguade M.
    Mol. Ecol. 17:1211-1223(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB1GV49_ARATH
AccessioniPrimary (citable) accession number: B1GV49
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: April 1, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.