Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

N-acylsphingosine amidohydrolase 1

Gene

ASAH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ceramidase activity Source: Ensembl

GO - Biological processi

  1. lung development Source: Ensembl
  2. response to organic substance Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Protein family/group databases

MEROPSiC89.001.

Names & Taxonomyi

Protein namesi
Submitted name:
N-acylsphingosine amidohydrolase 1Imported
Gene namesi
Name:ASAH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiB1B5Q0.

Expressioni

Gene expression databases

BgeeiB1B5Q0.
ExpressionAtlasiB1B5Q0. baseline and differential.

Interactioni

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000007253.
HOVERGENiHBG050586.

Family and domain databases

InterProiIPR029130. Acid_ceramidase_N.
IPR029132. CBAH/NAAA_C.
[Graphical view]
PfamiPF02275. CBAH. 1 hit.
PF15508. NAAA-beta. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B1B5Q0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
YRGAVPWYTI NLDLPPYKRW HELMLDKAPV LKVIVNSLKN MINTFVPSGK
60 70 80 90 100
IMQVVDEKLP GLLGNFPGPF EEEMKGIAAV TDIPLGEIIS FNIFYELFTI
110 120 130 140 150
CTSIVAEDKK GHLIHGRNMD FGVFLGWNIN NDTWVITEQL KPLTVNLDFQ
160 170 180 190 200
RNNKTVFKAS SFAGYVGMLT GFKPGLFSLT LNERFSINGG YLGILEWILG
210
KKDVMWIGFL TRTVLENST
Length:219
Mass (Da):24,768
Last modified:April 29, 2008 - v1
Checksum:iD0BF0EBDD5EBD2E4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei219 – 2191Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB371372 Genomic DNA. Translation: BAG12323.1.
AB371384 Genomic DNA. Translation: BAG12343.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB371372 Genomic DNA. Translation: BAG12323.1.
AB371384 Genomic DNA. Translation: BAG12343.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiB1B5Q0.

Protein family/group databases

MEROPSiC89.001.

Proteomic databases

PRIDEiB1B5Q0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000007253.
HOVERGENiHBG050586.

Miscellaneous databases

ChiTaRSiASAH1. human.
NextBioi35467038.

Gene expression databases

BgeeiB1B5Q0.
ExpressionAtlasiB1B5Q0. baseline and differential.

Family and domain databases

InterProiIPR029130. Acid_ceramidase_N.
IPR029132. CBAH/NAAA_C.
[Graphical view]
PfamiPF02275. CBAH. 1 hit.
PF15508. NAAA-beta. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Kim H., Satta Y.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sample-002aImported and Sample-012aImported.
  2. "Population genetic analysis of the N-acylsphingosine amidohydrolase gene associated with mental activity in humans."
    Kim H.L., Satta Y.
    Genetics 178:1505-1515(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sample-002aImported and Sample-012aImported.

Entry informationi

Entry nameiB1B5Q0_HUMAN
AccessioniPrimary (citable) accession number: B1B5Q0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: November 26, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.