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Protein
Submitted name:

Paired box protein Pax-6

Gene

PAX6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-6Imported
Gene namesi
Name:PAX6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000007372.20
HGNCiHGNC:8620 PAX6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000007372

PTM / Processingi

Proteomic databases

PeptideAtlasiB1B1J0

Expressioni

Gene expression databases

BgeeiENSG00000007372
ExpressionAtlasiB1B1J0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1B1J0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 144PairedInterPro annotationAdd BLAST141

Keywords - Domaini

Paired boxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0849 Eukaryota
ENOG410XS01 LUCA
GeneTreeiENSGT00680000099553
HOGENOMiHOG000230939

Family and domain databases

CDDicd00131 PAX, 1 hit
Gene3Di1.10.10.102 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001523 Paired_dom
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00292 PAX, 1 hit
PRINTSiPR00027 PAIREDBOX
SMARTiView protein in SMART
SM00351 PAX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51057 PAIRED_2, 1 hit

Sequencei

Sequence statusi: Fragment.

B1B1J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNSHSGVNQ LGGVFVNGRP LPDSTRQKIV ELAHSGARPC DISRILQTHA
60 70 80 90 100
DAKVQVLDNQ NVSNGCVSKI LGRYYETGSI RPRAIGGSKP RVATPEVVSK
110 120 130 140 150
IAQYKRECPS IFAWEIRDRL LSEGVCTNDN IPSVSSINRV LRNLASEKQQ
160 170 180 190 200
MGADGMYDKL RMLNGQTGSW GTRPGWYPGT SVPGQPTQDG CQQQEGGGEN
210 220 230 240
TNSISSNGED SDEAQMRLQL KRKLQRNRTS FTQEQIEALE K
Length:241
Mass (Da):26,515
Last modified:June 7, 2017 - v2
Checksum:i2B705903DF5BA935
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei241Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83307 Genomic DNA No translation available.
Z95332 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000455099; ENSP00000397384; ENSG00000007372
UCSCiuc058acc.1 human

Similar proteinsi

Entry informationi

Entry nameiB1B1J0_HUMAN
AccessioniPrimary (citable) accession number: B1B1J0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: June 7, 2017
Last modified: April 25, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported