Myosin light chain kinase, smooth muscle

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATP binding Source: InterPro
• myosin light chain kinase activity Source: Ensembl

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• aorta smooth muscle tissue morphogenesis Source: Ensembl
• bleb assembly Source: Ensembl
• cellular hypotonic response Source: Ensembl
• positive regulation of calcium ion transport Source: Ensembl
• positive regulation of cell migration Source: Ensembl
• positive regulation of wound healing Source: Ensembl

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• cleavage furrow Source: Ensembl
• cytoplasm Source: Ensembl
• extracellular exosome Source: Ensembl
• lamellipodium Source: Ensembl
• stress fiber Source: Ensembl

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the ‘Sequence’ section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MSGQLPGKTM GDVKLFASSH MSKTSHSVDP SKVSSMPLTE APAFILPPRN 
        60         70         80         90        100
LCVKEGATAK FEGRVRGYPE PQVTWHRKGQ AITNGGRFLL DCGVRGTFSL 
       110        120        130        140        150
VIHTVREEDK GKYTCEASNG SGARQVTVEL TVEGNSMKKR DQPVLSKASG 
       160        170        180        190        200
FPGETRPSIW GECPPKFATK LGRAVVKEGQ MGRFSCKITG RPPPQVTWLK 
       210        220        230        240        250
GNVPLQPSAR VSMSEKNGMQ ILEIRGVTRD DLGVYTCMVV NGSGKASMSA 
       260        270        280        290        300
ELSIPGLDNA ARLAVRGTKA PSPDIRKEVT NGVSKDPETV AESKNCPSPQ 
       310        320        330        340        350
RSGSSARATN SHLKSPQEPK PKLCEDAPRK VPQSSILQKS TSTITLQALK 
       360        370        380        390        400
VQPEARVPAI GSFSPGEDRK SLAAPQQATL PTRQSSLGGS VGNKFVTGNI 
       410        420        430        440        450
PRESQRESTF PRFESQPQSQ EVTEGQTVKF ICEVSGIPKP DVGWFLEGIP 
       460        470        480        490        500
VRRREGITEV YEDGVSHHLC LLRARTRDSG RYSCTASNSL GQVSCSWSLL 
       510        520        530        540        550
VDRPNLAQTA PSFSSVLKDS VVIEGQDFVL RCSVQGTPAP RVTWLLNGQP 
       560        570        580        590        600
IQFAHSICEA GVAELHIQDA LPEDRGTYTC LAENAMGQVS CSATVTVQEK 
       610        620        630        640        650
KGEGEREHRL SPARSKPIAP IFLQGLSDLK VMDGSQVTMT VQVSGNPPPE 
       660        670        680        690        700
VIWLHDGNEI QESEDFHFEQ KGGWHSLCIQ EVFPEDTGTY TCEAWNSAGE 
       710        720        730        740        750
VRTRAVLTVQ EPHDGTQPWF ISKPRSVTAT LGQSVLISCA IAGDPFPTVH 
       760        770        780        790        800
WLRDGRALSK DSGHFELLQN EDVFTLVLKN VQPWHAGQYE ILLKNRVGEC 
       810        820        830        840        850
SCQVSLMLHN SPSRAPPRGR EPASCEGLCG GGGVGAHGDG DRHGTLRPCW 
       860        870        880        890        900
PARGQGWPEE EDGEDVRGLL KRRVETRLHT EEAIRQQEVG QLDFRDLLGK 
       910        920        930        940        950
KVSTKTVSED DLKDIPAEQM DFRANLQRQV KPKTISEEER KVHSPQQVDF 
       960        970        980        990       1000
RSVLAKKGTP KTPVPEKAPP KAATPDFRSV LGGKKKSPSE NGGNSAEVLN 
      1010       1020       1030       1040       1050
VKAGESPTPA GDAQAIGALK PVGNAKPAET PKPIGNAKPT ETLKPVGNTK 
      1060       1070       1080       1090       1100
PAETLKPIAN AQPSGSLKPV TNAQPAEPQK PVGNAKSAET SKPAGKEEVK 
      1110       1120       1130       1140       1150
EVKNDVNCKK GQVGATGNEK RPESQGSAPV FKEKLQDVHV AEGEKLLLQC 
      1160       1170       1180       1190       1200
QVISDPPATV TWSLNGKTLK TTKFIVLAQE GSRFSVSIEK ALPEDRGLYK 
      1210       1220       1230       1240       1250
CVAKNSAGQA ECSCQVTVDD AQTSENTKAP EMKSRRPKSS LPPVLGTESD 
      1260       1270       1280       1290       1300
ATVKKKPAPK TPTKAAMPPQ IIQFPEDQKV RAGEPVELFG KVAGTQPITC 
      1310       1320       1330       1340       1350
KWMKFRKQIQ ESEHIKVENG ESGSKLTILA ARQEHCGCYT LVVENKLGSR 
      1360       1370       1380       1390       1400
QAQVNLTVVD KPDPPAGTPC ASDIRSSSLT LSWYGSSYDG GSAVQSYNVE 
      1410       1420       1430       1440       1450
IWDTEDKVWK ELATCRSTSF NVQDLLPDRE YKFRVRAVNV YGTSEPSQES 
      1460       1470       1480       1490       1500
ELTAVGEKPE EPKDEVEVSD DDEKEPEVDY RTVTVNTEQK VSDVYDIEER 
      1510       1520       1530       1540       1550
LGSGKFGQVF RLVEKKTGKI WAGKFFKAYS AKEKDNIRQE ISIMNCLHHP 
      1560       1570       1580       1590       1600
KLVQCVDAFE EKANIVMVLE IVSGGELFER IIDEDFELTE RECIKYMRQI 
      1610       1620       1630       1640       1650
SEGVEYIHKQ GIVHLDLKPE NIMCVNKTGT RIKLIDFGLA RRLENAGSLK 
      1660       1670       1680       1690       1700
VLFGTPEFVA PEVINYEPIG YATDMWSIGV ICYILVSGLS PFMGDNDNET 
      1710       1720       1730       1740       1750
LANVTSATWD FDDEAFDEIS DDAKDFISNL LKKDMKNRLD CTQCLQHPWL 
      1760       1770       1780       1790       1800
MKDTKNMEAK KLSKDRMKKY MARRKWQKTG NAVRAIGRLS SMAMISGLSG 
      1810       1820       1830       1840       1850
RKSSTGSPTS PINAEKLESE DDVSQAFLEA VAEEKPHVKP YFSKTIRDLE 
      1860       1870       1880       1890       1900
VVEGSAARFD CKIEGYPDPE VVWFKDDQSI RESRHFQIDY DEDGNCSLII 
      1910       1920       1930       1940       1950
SDVCGDDDAK YTCKAVNSLG EATCTAELIV ETMEEGEGEE GGEEEEEEEE 

Sequence databases

Genome annotation databases

<p>This section provides links to the UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ