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B1B0D4

- B1B0D4_HUMAN

UniProt

B1B0D4 - B1B0D4_HUMAN

Protein
Submitted name:

ADAMTS-like protein 2

Gene

ADAMTSL2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro
    2. zinc ion binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ADAMTS-like protein 2Imported
    Gene namesi
    Name:ADAMTSL2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:14631. ADAMTSL2.

    Subcellular locationi

    GO - Cellular componenti

    1. proteinaceous extracellular matrix Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiB1B0D4.

    Expressioni

    Gene expression databases

    ArrayExpressiB1B0D4.

    Structurei

    3D structure databases

    ProteinModelPortaliB1B0D4.
    SMRiB1B0D4. Positions 159-345.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    OMAiNRTCTGT.
    PhylomeDBiB1B0D4.

    Family and domain databases

    InterProiIPR010294. ADAM_spacer1.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR010909. PLAC.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF05986. ADAM_spacer1. 1 hit.
    PF08686. PLAC. 1 hit.
    PF00090. TSP_1. 5 hits.
    [Graphical view]
    PRINTSiPR01857. ADAMTSFAMILY.
    SMARTiSM00209. TSP1. 7 hits.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 7 hits.
    PROSITEiPS50900. PLAC. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1B0D4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLFEVGEGGG AGEEGKGRGR PGRSLCTHAA PARTAHLAPS ALRSARPFLW     50
    EDNLLTRSQG LPDNHDQLVP DNLEAWALAG PRGLFPKRTL VIWKRIGAGL 100
    VVTVALLPRM DGRWQCSCWA WFLLVLAVVA GDTVSTGSTD NSPTSNSLEG 150
    GTDATAFWWG EWTKWTACSR SCGGGVTSQE RHCLQQRRKS VPGPGNRTCT 200
    GTSKRYQLCR VQECPPDGRS FREEQCVSFN SHVYNGRTHQ WKPLYPDDYV 250
    HISSKPCDLH CTTVDGQRQL MVPARDGTSC KLTDLRGVCV SGKCEPIGCD 300
    GVLFSTHTLD KCGICQGDGS SCTHVTGNYR KGNAHLGYSL VTHIPAGARD 350
    IQIVERKKSA DVLALADEAG YYFFNGNYKV DSPKNFNIAG TVVKYRRPMD 400
    VYETGIEYIV AQGPTNQGLN VMVWNQNGKS PSITFEYTLL QPPHESRPQP 450
    IYYGFSESAE SQGLDGAGLM GFVPHNGSLY GQASSERLGL DNRLFGHPGL 500
    DMELGPSQGQ ETNEVCEQAG GGACEGPPRG KGFRDRNVTG TPLTGDKDDE 550
    EVDTHFASQE FFSANAISDQ LLGAGSDLKD FTLNETVNSI FAQGAPRSSL 600
    AESFFVDYEE NEGAGPYLLN GSYLELSSDR VANSSSEAPF PNVSTSLLTS 650
    AGNRTHKART RPKARKQGVS PADMYRWKLS SHEPCSATCT TGVMSAYAMC 700
    VRYDGVEVDD SYCDALTRPE PVHEFCAGRE CQPRWETSSW SECSRTCGEG 750
    YQFRVVRCWK MLSPGFDSSV YSDLCEAAEA VRPEERKTCR NPACGPQWEM 800
    SEWSECTAKC GERSVVTRDI RCSEDEKLCD PNTRPVGEKN CTGPPCDRQW 850
    TVSDWGPCSG SCGQGRTIRH VYCKTSDGRV VPESQCQMET KPLAIHPCGD 900
    KNCPAHWLAQ DWERCNTTCG RGVKKRLVLC MELANGKPQT RSGPECGLAK 950
    KPPEESTCFE RPCFKWYTSP WSECTKTCGV GVRMRDVKCY QGTDIVRGCD 1000
    PLVKPVGRQA CDLQPCPTEP PDDSCQDQPG TNCALAIKVN LCGHWYYSKA 1050
    CCRSCRPPHS 1060
    Length:1,060
    Mass (Da):116,285
    Last modified:April 8, 2008 - v1
    Checksum:i341D2A3CEB1C5427
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX324209 Genomic DNA. No translation available.
    BX629352 Genomic DNA. No translation available.
    BX649571 Genomic DNA. No translation available.
    RefSeqiXP_005272294.1. XM_005272237.1.
    UniGeneiHs.522543.

    Genome annotation databases

    EnsembliENST00000393061; ENSP00000376781; ENSG00000197859.
    GeneIDi9719.
    KEGGihsa:9719.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX324209 Genomic DNA. No translation available.
    BX629352 Genomic DNA. No translation available.
    BX649571 Genomic DNA. No translation available.
    RefSeqi XP_005272294.1. XM_005272237.1.
    UniGenei Hs.522543.

    3D structure databases

    ProteinModelPortali B1B0D4.
    SMRi B1B0D4. Positions 159-345.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B1B0D4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000393061 ; ENSP00000376781 ; ENSG00000197859 .
    GeneIDi 9719.
    KEGGi hsa:9719.

    Organism-specific databases

    CTDi 9719.
    HGNCi HGNC:14631. ADAMTSL2.
    GenAtlasi Search...

    Phylogenomic databases

    OMAi NRTCTGT.
    PhylomeDBi B1B0D4.

    Miscellaneous databases

    ChiTaRSi ADAMTSL2. human.
    GenomeRNAii 9719.
    NextBioi 35466988.

    Gene expression databases

    ArrayExpressi B1B0D4.

    Family and domain databases

    InterProi IPR010294. ADAM_spacer1.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR010909. PLAC.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF05986. ADAM_spacer1. 1 hit.
    PF08686. PLAC. 1 hit.
    PF00090. TSP_1. 5 hits.
    [Graphical view ]
    PRINTSi PR01857. ADAMTSFAMILY.
    SMARTi SM00209. TSP1. 7 hits.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 7 hits.
    PROSITEi PS50900. PLAC. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (AUG-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB1B0D4_HUMAN
    AccessioniPrimary (citable) accession number: B1B0D4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3