Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B1AYL0 (B1AYL0_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Scn9a Ensembl ENSMUSP00000107973 MGI 107636
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000107973
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length1973 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein By similarity RuleBase RU003809.

Sequence similarities

Belongs to the sodium channel family. RuleBase RU003809

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000107973

Sequences

Sequence LengthMass (Da)Tools
B1AYL0 [UniParc].

Last modified April 8, 2008. Version 1.
Checksum: 2317EF807F7A2C9C

FASTA1,973224,667
        10         20         30         40         50         60 
MAMLPPPGPQ SFVHFTKQSL ALIEQRISEE KAKGHKDEKK DDEEEGPKPS SDLEAGKQLP 

        70         80         90        100        110        120 
FIYGDIPPGM VSEPLEDLDP YYADKKTFIV LNKGKAIFRF NATPALYMLS PFSPLRRISI 

       130        140        150        160        170        180 
KILVHSLFSM LIMCTILTNC IFMTMSNPPD WTKNVEYTFT GIYTFESLIK ILARGFCVGE 

       190        200        210        220        230        240 
FTFLRDPWNW LDFVVIVFAY LTEFVNLGNV SALRTFRVLR ALKTISVIPG LKTIVGALIQ 

       250        260        270        280        290        300 
SVKKLSDVMI LTVFCLSVFA LIGLQLFMGN LKHKCFRKDL EQNETLESIM STAESEEELK 

       310        320        330        340        350        360 
RYFYYLEGSK DALLCGFSTD SGQCPEGYEC VTAGRNPDYG YTSFDTFGWA FLALFRLMTQ 

       370        380        390        400        410        420 
DYWENLYQQT LRAAGKTYMI FFVVVIFLGS FYLINLILAV VAMAYEEQNQ ANIEEAKQKE 

       430        440        450        460        470        480 
LEFQQMLDRL KKEQEEAEAI AAAAAEYTSL GRSRIMGLSE SSSETSRLSS KSAKERRNRR 

       490        500        510        520        530        540 
KKKKQKLSSG EEKGDDEKLS KSGSEESIRK KSFHLGVEGH HRAREKRLST PNQSPLSIRG 

       550        560        570        580        590        600 
SLFSARRSSR TSLFSFKGRG RDLGSETEFA DDEHSIFGDN ESRRGSLFVP HRPRERRSSN 

       610        620        630        640        650        660 
ISQASRSPPV LPVNGKMHSA VDCNGVVSLV DGPSALMLPN GQLLPEGTTN QMRKKRLSSS 

       670        680        690        700        710        720 
YFLSEDMLND PHLRQRAMSR ASILTNTVEE LEESRQKCPP WWYRFAHTFL IWNCSPYWIK 

       730        740        750        760        770        780 
FKKFIYFIVM DPFVDLAITI CIVLNTLFMA MEHHPMTDEF KNVLAVGNLV FTGIFAAEMV 

       790        800        810        820        830        840 
LKLIAMDPYE YFQVGWNIFD SLIVTLSLVE LFLADVEGLS VLRSFRLLRV FKLAKSWPTL 

       850        860        870        880        890        900 
NMLIKIIGNS VGALGNLTLV LAIIVFIFAV VGMQLFGKSY KECVCKINEN CKLPRWHMND 

       910        920        930        940        950        960 
FFHSFLIVFR VLCGEWIETM WDCMEVAGQT MCLIVYMMVM VIGNLVVLNL FLALLLSSFS 

       970        980        990       1000       1010       1020 
SDNLTAIEED TDANNLQIAV ARIKRGINYV KQTLREFILK SFSKKPKGSK DTKRTADPNN 

      1030       1040       1050       1060       1070       1080 
KRENYISNRT LAEISKDHNF LKEKDKISGF SSSLDKSFMD ENDYQSFIHN PSLTVTVPIA 

      1090       1100       1110       1120       1130       1140 
PGESDLENMN TEELSSDSDS DYSKERRNRS SSSECSTVDN PLPGEEEAEA EPINADEPEA 

      1150       1160       1170       1180       1190       1200 
CFTDGCVRRF PCCQVNIDSG KGKVWWTIRK TCYRIVEHSW FESFIVLMIL LSSGALAFED 

      1210       1220       1230       1240       1250       1260 
IYIEKKKTIK IILEYADKIF TYIFILEMLL KWVAYGYKTY FTNAWCWLDF LIVDVSLVTL 

      1270       1280       1290       1300       1310       1320 
VANTLGYSDL GPIKSLRTLR ALRPLRALSR FEGMRVVVNA LIGAIPSIMN VLLVCLIFWL 

      1330       1340       1350       1360       1370       1380 
IFSIMGVNLF AGKFYECVNT TDGSRFSVSQ VANRSECFAL MNVSGNVRWK NLKVNFDNVG 

      1390       1400       1410       1420       1430       1440 
LGYLSLLQVA TFKGWMDIMY AAVDSVNVNA QPIYEYNLYM YIYFVIFIIF GSFFTLNLFI 

      1450       1460       1470       1480       1490       1500 
GVIIDNFNQQ KKKLGGQDIF MTEEQKKYYN AMKKLGSKKP QKPIPRPGNK FQGCIFDLVT 

      1510       1520       1530       1540       1550       1560 
NQAFDITIMV LICLNMVTMM VEKEGQTDYM SFVLYWINVV FIILFTGECV LKLISLRHYY 

      1570       1580       1590       1600       1610       1620 
FTVGWNIFDF VVVILSIVGM FLAEMIEKYF VSPTLFRVIR LARIGRILRL IKGAKGIRTL 

      1630       1640       1650       1660       1670       1680 
LFALMMSLPA LFNIGLLLFL VMFIYAIFGM SNFAYVKKEA GINDMFNFET FGNSMICLFQ 

      1690       1700       1710       1720       1730       1740 
ITTSAGWDGL LAPILNSAPP DCDPKKVHPG SSVEGDCGNP SVGIFYFVSY IIISFLVVVN 

      1750       1760       1770       1780       1790       1800 
MYIAVILENF SVATEESTEP LSEDDFEMFY EVWEKFDPDA TQFIEFCKLS DFAAALDPPL 

      1810       1820       1830       1840       1850       1860 
LIAKPNKVQL IAMDLPMVSG DRIHCLDILF AFTKRVLGES GEMDSLRSQM EERFMSANPS 

      1870       1880       1890       1900       1910       1920 
KVSYEPITTT LKRKQEDVSA TIIQRAYRRY RLRQNVKNIS SIYIKDGDRD DDLPNKEDIV 

      1930       1940       1950       1960       1970 
FDNVNENSSP EKTDATASTI SPPSYDSVTK PDQEKYETDK TEKEDKEKDE SRK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL928623 Genomic DNA. No translation available.
AL928726 Genomic DNA. No translation available.
RefSeqXP_006499098.1. XM_006499035.1.
UniGeneMm.440889.

3D structure databases

ProteinModelPortalB1AYL0.
SMRB1AYL0. Positions 1748-1903.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000112354; ENSMUSP00000107973; ENSMUSG00000075316.
GeneID20274.

Organism-specific databases

MGIMGI:107636. Scn9a.

Phylogenomic databases

GeneTreeENSGT00560000076721.
HOGENOMHOG000231755.
HOVERGENHBG053100.

Family and domain databases

Gene3D1.20.120.350. 4 hits.
InterProIPR027359. Channel_four-helix_dom.
IPR024583. DUF3451.
IPR005821. Ion_trans_dom.
IPR000048. IQ_motif_EF-hand-BS.
IPR001696. Na_channel_asu.
IPR010526. Na_trans_assoc.
IPR028803. SCN9A.
[Graphical view]
PANTHERPTHR10037:SF28. PTHR10037:SF28. 1 hit.
PfamPF11933. DUF3451. 1 hit.
PF00520. Ion_trans. 4 hits.
PF06512. Na_trans_assoc. 1 hit.
[Graphical view]
PRINTSPR00170. NACHANNEL.
SMARTSM00015. IQ. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35546306.
SOURCESearch...

Entry information

Entry nameB1AYL0_MOUSE
AccessionPrimary (citable) accession number: B1AYL0
Entry history
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: April 16, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)