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Protein
Submitted name:

Ribosomal protein S6 kinase alpha-3

Gene

Rps6ka3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Ribosomal protein S6 kinase alpha-3Imported
Gene namesi
Name:Rps6ka3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:104557. Rps6ka3.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiB1AXN9.
PaxDbiB1AXN9.
PeptideAtlasiB1AXN9.
PRIDEiB1AXN9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000031309.
ExpressionAtlasiB1AXN9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB1AXN9.
SMRiB1AXN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 299Protein kinaseInterPro annotationAdd BLAST260
Domaini300 – 369AGC-kinase C-terminalInterPro annotationAdd BLAST70
Domaini394 – 651Protein kinaseInterPro annotationAdd BLAST258

Phylogenomic databases

eggNOGiKOG0598. Eukaryota.
ENOG410XNPH. LUCA.
GeneTreeiENSGT00890000139324.
HOGENOMiHOG000233033.
HOVERGENiHBG108317.

Family and domain databases

InterProiView protein in InterPro
IPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR016239. Ribosomal_S6_kinase_II.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 2 hits.
PF00433. Pkinase_C. 1 hit.
PIRSFiPIRSF000606. Ribsml_S6_kin_2. 1 hit.
SMARTiView protein in SMART
SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 2 hits.
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiView protein in PROSITE
PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 2 hits.
PS50011. PROTEIN_KINASE_DOM. 2 hits.
PS00108. PROTEIN_KINASE_ST. 2 hits.

Sequencei

Sequence statusi: Complete.

B1AXN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEPMGEEEI NPQTEEGSIK EIAITHHVKE GHEKADPSQF ELLKVLGQGS
60 70 80 90 100
FGKVFLVKKI SGSDARQLYA MKVLKKATLK VRDRVRTKME RDILVEVNHP
110 120 130 140 150
FIVKLHYAFQ TEGKLYLILD FLRGGDLFTR LSKEVMFTEE DVKFYLAELA
160 170 180 190 200
LALDHLHSLG IIYRDLKPEN ILLDEEGHIK LTDFGLSKES IDHEKKAYSF
210 220 230 240 250
CGTVEYMAPE VVNRRGHTQS ADWWSFGVLM FEMLTGTLPF QGKDRKETMT
260 270 280 290 300
MILKAKLGMP QFLSPEAQSL LRMLFKRNPA NRLGAGPDGV EEIKRHSFFS
310 320 330 340 350
TIDWNKLYRR EIHPPFKPAT GRPEDTFYFD PEFTAKTPKD SPGIPPSANA
360 370 380 390 400
HQLFRGFSFV AITSDDESQA MQTVGVHSIV QQLHRNSIQF TDGYEVKEDI
410 420 430 440 450
GVGSYSVCKR CIHKATNMEF AVKIIDKSKR DPTEEIEILL RYGQHPNIIT
460 470 480 490 500
LKDVYDDGKY VYVVTELMKG GELLDKILRQ KFFSEREASA VLFTITKTVE
510 520 530 540 550
YLHAQGVVHR DLKPSNILYV DESGNPESIR ICDFGFAKQL RAENGLLMTP
560 570 580 590 600
CYTANFVAPE VLKRQGYDAA CDIWSLGVLL YTMLTGYTPF ANGPDDTPEE
610 620 630 640 650
ILARIGSGKF SLSGGYWNSV SDTAKDLVSK MLHVDPHQRL TAALVLRHPW
660 670 680 690 700
IVHWDQLPQY QLNRQDAPHL VKGAMAATYS ALNRNQSPVL EPVGRSTLAQ
710
RRGIKKITST AL
Length:712
Mass (Da):80,670
Last modified:April 8, 2008 - v1
Checksum:i7156B8A0F3BECB3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671881 Genomic DNA. No translation available.
AL808146 Genomic DNA. No translation available.
RefSeqiNP_001333604.1. NM_001346675.1.
XP_006528750.1. XM_006528687.1.
XP_017173843.1. XM_017318354.1.
XP_017173844.1. XM_017318355.1.
UniGeneiMm.328476.
Mm.392829.

Genome annotation databases

EnsembliENSMUST00000112493; ENSMUSP00000108112; ENSMUSG00000031309.
GeneIDi110651.

Similar proteinsi

Entry informationi

Entry nameiB1AXN9_MOUSE
AccessioniPrimary (citable) accession number: B1AXN9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 25, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported