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Protein

Non-specific serine/threonine protein kinase

Gene

Rps6ka3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei165Proton acceptorUniRule annotation1
Active sitei511Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:Rps6ka3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:104557 Rps6ka3

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiB1AXN9
PeptideAtlasiB1AXN9
PRIDEiB1AXN9

Expressioni

Gene expression databases

BgeeiENSMUSG00000031309
ExpressionAtlasiB1AXN9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1AXN9
SMRiB1AXN9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 299Protein kinaseInterPro annotationAdd BLAST260
Domaini300 – 369AGC-kinase C-terminalInterPro annotationAdd BLAST70
Domaini394 – 651Protein kinaseInterPro annotationAdd BLAST258

Phylogenomic databases

eggNOGiKOG0598 Eukaryota
ENOG410XNPH LUCA
GeneTreeiENSGT00890000139324
HOGENOMiHOG000233033
HOVERGENiHBG108317

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR016239 Ribosomal_S6_kinase_II
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 2 hits
PF00433 Pkinase_C, 1 hit
PIRSFiPIRSF000606 Ribsml_S6_kin_2, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 2 hits
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

Sequencei

Sequence statusi: Complete.

B1AXN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEPMGEEEI NPQTEEGSIK EIAITHHVKE GHEKADPSQF ELLKVLGQGS
60 70 80 90 100
FGKVFLVKKI SGSDARQLYA MKVLKKATLK VRDRVRTKME RDILVEVNHP
110 120 130 140 150
FIVKLHYAFQ TEGKLYLILD FLRGGDLFTR LSKEVMFTEE DVKFYLAELA
160 170 180 190 200
LALDHLHSLG IIYRDLKPEN ILLDEEGHIK LTDFGLSKES IDHEKKAYSF
210 220 230 240 250
CGTVEYMAPE VVNRRGHTQS ADWWSFGVLM FEMLTGTLPF QGKDRKETMT
260 270 280 290 300
MILKAKLGMP QFLSPEAQSL LRMLFKRNPA NRLGAGPDGV EEIKRHSFFS
310 320 330 340 350
TIDWNKLYRR EIHPPFKPAT GRPEDTFYFD PEFTAKTPKD SPGIPPSANA
360 370 380 390 400
HQLFRGFSFV AITSDDESQA MQTVGVHSIV QQLHRNSIQF TDGYEVKEDI
410 420 430 440 450
GVGSYSVCKR CIHKATNMEF AVKIIDKSKR DPTEEIEILL RYGQHPNIIT
460 470 480 490 500
LKDVYDDGKY VYVVTELMKG GELLDKILRQ KFFSEREASA VLFTITKTVE
510 520 530 540 550
YLHAQGVVHR DLKPSNILYV DESGNPESIR ICDFGFAKQL RAENGLLMTP
560 570 580 590 600
CYTANFVAPE VLKRQGYDAA CDIWSLGVLL YTMLTGYTPF ANGPDDTPEE
610 620 630 640 650
ILARIGSGKF SLSGGYWNSV SDTAKDLVSK MLHVDPHQRL TAALVLRHPW
660 670 680 690 700
IVHWDQLPQY QLNRQDAPHL VKGAMAATYS ALNRNQSPVL EPVGRSTLAQ
710
RRGIKKITST AL
Length:712
Mass (Da):80,670
Last modified:April 8, 2008 - v1
Checksum:i7156B8A0F3BECB3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL671881 Genomic DNA No translation available.
AL808146 Genomic DNA No translation available.
RefSeqiNP_001333604.1, NM_001346675.1
XP_006528750.1, XM_006528687.1
XP_017173843.1, XM_017318354.1
XP_017173844.1, XM_017318355.1
UniGeneiMm.328476
Mm.392829

Genome annotation databases

EnsembliENSMUST00000112493; ENSMUSP00000108112; ENSMUSG00000031309
GeneIDi110651

Similar proteinsi

Entry informationi

Entry nameiB1AXN9_MOUSE
AccessioniPrimary (citable) accession number: B1AXN9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health