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B1AWI7

- B1AWI7_MOUSE

UniProt

B1AWI7 - B1AWI7_MOUSE

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Protein
Submitted name:

Atrial natriuretic peptide receptor 2

Gene
Npr2
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. guanylate cyclase activity Source: MGI
  3. identical protein binding Source: MGI
  4. natriuretic peptide receptor activity Source: MGI
  5. protein kinase activity Source: InterPro

GO - Biological processi

  1. bone development Source: MGI
  2. cGMP biosynthetic process Source: MGI
  3. intracellular signal transduction Source: InterPro
  4. negative regulation of meiotic cell cycle Source: MGI
  5. negative regulation of oocyte maturation Source: MGI
  6. single organism reproductive process Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Atrial natriuretic peptide receptor 2Imported
Gene namesi
Name:Npr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:97372. Npr2.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiB1AWI7.

Expressioni

Gene expression databases

ArrayExpressiB1AWI7.

Structurei

3D structure databases

ProteinModelPortaliB1AWI7.
SMRiB1AWI7. Positions 24-442, 503-832, 850-963.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00710000106571.
HOVERGENiHBG051862.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR001828. ANF_lig-bd_rcpt.
IPR011009. Kinase-like_dom.
IPR001170. Ntpep_rcpt.
IPR028082. Peripla_BP_I.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSiPR00255. NATPEPTIDER.
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.
SSF55073. SSF55073. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00458. ANF_RECEPTORS. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1AWI7-1 [UniParc]FASTAAdd to Basket

« Hide

MALPSLLLVV AALAGGVRPP GARNLTLAVV LPEHNLSYAW AWPRVGPAVA     50
LAVEALGRAL PVDLRFVSSE LDGACSEYLA PLRAVDLKLY HDPDLLLGPG 100
CVYPAASVAR FASHWRLPLL TAGAVASGFA AKNEHYRTLV RTGPSAPKLG 150
EFVVTLHGHF NWTARAALLY LDARTDDRPH YFTIEGVFEA LQGSNLSVQH 200
QVYAREPGGP EQATHFIRAN GRIVYICGPL EMLHEILLQA QRENLTNGDY 250
VFFYLDVFGE SLRAGPTRAT GRPWQDNRTQ EQAQALREAF QTVLVITYRE 300
PPNPEYQEFQ NRLLIRARED FGVELAPSLM NLIAGCFYDG ILLYAQVLNE 350
TIQEGGTRED GLRIVEKMQG RRYHGVTGLV VMDKNNDRET DFVLWAMGDL 400
DSGDFQPAAH YSGAEKQIWW TGRPIPWVKG APPLDNPPCA FDLDDPSCDK 450
TPLSTLAIVA LGTGVTFIMF GVSSFLIFRK LMLEKELASM LWRIRWEELQ 500
FGNSDRYHKG AGSRLTLSLR GSSYGSLMTA HGKYQIFANT GHFKGNVVAI 550
KHVNKKRIEL TRQVLFELKH MRDVQFNHLT RFIGACIDPP NICIVTEYCP 600
RGSLQDILEN DSINLDWMFR YSLINDLVKG MAFLHNSIIS SHGSLKSSNC 650
VVDSRFVLKI TDYGLASFRS TAEPDDSHAL YAKKLWTAPE LLSGNPLPTT 700
GMQKADVYSF AIILQEIALR SGPFYLEGLD LSPKEIVQKV RNGQRPYFRP 750
SIDRTQLNEE LVLLMERCWA QDPTERPDFG QIKGFIRRFN KEGGTSILDN 800
LLLRMEQYAN NLEKLVEERT QAYLEEKRKA EALLYQILPH SVAEQLKRGE 850
TVQAEAFDSV TIYFSDIVGF TALSAESTPM QVVTLLNDLY TCFDAIIDNF 900
DVYKVETIGD AYMVVSGLPG RNGQRHAPEI ARMALALLDA VSSFRIRHRP 950
HDQLRLRIGV HTGKADSHLA LVSTFPDLSQ PVCFYRASLC WGGWPEDAPV 1000
LSFWRHSKHC FSNGVEWPSS KDPCLLDHQG RPG 1033
Length:1,033
Mass (Da):115,772
Last modified:April 8, 2008 - v1
Checksum:i87F1DA1FD1641ABF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL732626 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000107874; ENSMUSP00000103506; ENSMUSG00000028469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL732626 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B1AWI7.
SMRi B1AWI7. Positions 24-442, 503-832, 850-963.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1AWI7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000107874 ; ENSMUSP00000103506 ; ENSMUSG00000028469 .

Organism-specific databases

MGIi MGI:97372. Npr2.

Phylogenomic databases

GeneTreei ENSGT00710000106571.
HOVERGENi HBG051862.

Miscellaneous databases

ChiTaRSi NPR2. mouse.
NextBioi 35546152.
SOURCEi Search...

Gene expression databases

ArrayExpressi B1AWI7.

Family and domain databases

Gene3Di 3.30.70.1230. 1 hit.
InterProi IPR001054. A/G_cyclase.
IPR001828. ANF_lig-bd_rcpt.
IPR011009. Kinase-like_dom.
IPR001170. Ntpep_rcpt.
IPR028082. Peripla_BP_I.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view ]
Pfami PF01094. ANF_receptor. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view ]
PRINTSi PR00255. NATPEPTIDER.
SMARTi SM00044. CYCc. 1 hit.
[Graphical view ]
SUPFAMi SSF53822. SSF53822. 1 hit.
SSF55073. SSF55073. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00458. ANF_RECEPTORS. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1AWI7_MOUSE
AccessioniPrimary (citable) accession number: B1AWI7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: July 9, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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