B1AWI7 (B1AWI7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Atrial natriuretic peptide receptor 2 Ensembl ENSMUSP00000103506

Gene names

Name:

Npr2 Ensembl ENSMUSP00000103506 MGI 97372

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000103506

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1033 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000103506

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	bone development Inferred from mutant phenotype PubMed 624676. Source: MGI intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro plasma membrane Traceable author statement PubMed 14514678. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro guanylate cyclase activity Inferred from direct assay PubMed 14514678. Source: MGI natriuretic peptide receptor activity Inferred from direct assay PubMed 14514678. Source: MGI protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1AWI7 [UniParc]. Last modified April 8, 2008. Version 1. Checksum: 87F1DA1FD1641ABF	FASTA	1,033	115,772
	10 20 30 40 50 60 MALPSLLLVV AALAGGVRPP GARNLTLAVV LPEHNLSYAW AWPRVGPAVA LAVEALGRAL 70 80 90 100 110 120 PVDLRFVSSE LDGACSEYLA PLRAVDLKLY HDPDLLLGPG CVYPAASVAR FASHWRLPLL 130 140 150 160 170 180 TAGAVASGFA AKNEHYRTLV RTGPSAPKLG EFVVTLHGHF NWTARAALLY LDARTDDRPH 190 200 210 220 230 240 YFTIEGVFEA LQGSNLSVQH QVYAREPGGP EQATHFIRAN GRIVYICGPL EMLHEILLQA 250 260 270 280 290 300 QRENLTNGDY VFFYLDVFGE SLRAGPTRAT GRPWQDNRTQ EQAQALREAF QTVLVITYRE 310 320 330 340 350 360 PPNPEYQEFQ NRLLIRARED FGVELAPSLM NLIAGCFYDG ILLYAQVLNE TIQEGGTRED 370 380 390 400 410 420 GLRIVEKMQG RRYHGVTGLV VMDKNNDRET DFVLWAMGDL DSGDFQPAAH YSGAEKQIWW 430 440 450 460 470 480 TGRPIPWVKG APPLDNPPCA FDLDDPSCDK TPLSTLAIVA LGTGVTFIMF GVSSFLIFRK 490 500 510 520 530 540 LMLEKELASM LWRIRWEELQ FGNSDRYHKG AGSRLTLSLR GSSYGSLMTA HGKYQIFANT 550 560 570 580 590 600 GHFKGNVVAI KHVNKKRIEL TRQVLFELKH MRDVQFNHLT RFIGACIDPP NICIVTEYCP 610 620 630 640 650 660 RGSLQDILEN DSINLDWMFR YSLINDLVKG MAFLHNSIIS SHGSLKSSNC VVDSRFVLKI 670 680 690 700 710 720 TDYGLASFRS TAEPDDSHAL YAKKLWTAPE LLSGNPLPTT GMQKADVYSF AIILQEIALR 730 740 750 760 770 780 SGPFYLEGLD LSPKEIVQKV RNGQRPYFRP SIDRTQLNEE LVLLMERCWA QDPTERPDFG 790 800 810 820 830 840 QIKGFIRRFN KEGGTSILDN LLLRMEQYAN NLEKLVEERT QAYLEEKRKA EALLYQILPH 850 860 870 880 890 900 SVAEQLKRGE TVQAEAFDSV TIYFSDIVGF TALSAESTPM QVVTLLNDLY TCFDAIIDNF 910 920 930 940 950 960 DVYKVETIGD AYMVVSGLPG RNGQRHAPEI ARMALALLDA VSSFRIRHRP HDQLRLRIGV 970 980 990 1000 1010 1020 HTGKADSHLA LVSTFPDLSQ PVCFYRASLC WGGWPEDAPV LSFWRHSKHC FSNGVEWPSS 1030 KDPCLLDHQG RPG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000103506.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000103506.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL732626 Genomic DNA. No translation available.
IPI	IPI00556825.
UniGene	Mm.103477.
3D structure databases
ProteinModelPortal	B1AWI7.
SMR	B1AWI7. Positions 24-442, 503-803, 850-963.
ModBase	Search...
Proteomic databases
PRIDE	B1AWI7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000107874; ENSMUSP00000103506; ENSMUSG00000028469.
Organism-specific databases
MGI	MGI:97372. Npr2.
Phylogenomic databases
GeneTree	ENSGT00560000076744.
HOVERGEN	HBG051862.
Gene expression databases
ArrayExpress	B1AWI7.
Family and domain databases
Gene3D	3.30.70.1230. 1 hit.
InterPro	IPR001054. A/G_cyclase. IPR001828. ANF_lig-bd_rcpt. IPR011009. Kinase-like_dom. IPR001170. Ntpep_rcpt. IPR000719. Prot_kinase_cat_dom. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. [Graphical view]
Pfam	PF01094. ANF_receptor. 1 hit. PF00211. Guanylate_cyc. 1 hit. PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
PRINTS	PR00255. NATPEPTIDER.
SMART	SM00044. CYCc. 1 hit. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 1 hit. SSF56112. Kinase_like. 1 hit.
PROSITE	PS00458. ANF_RECEPTORS. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NPR2. mouse.
NextBio	35546152.
SOURCE	Search...

Entry information

Entry name

B1AWI7_MOUSE

Accession

Primary (citable) accession number: B1AWI7

Entry history

Integrated into UniProtKB/TrEMBL:	April 8, 2008
Last sequence update:	April 8, 2008
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)