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B1AVY2

- B1AVY2_MOUSE

UniProt

B1AVY2 - B1AVY2_MOUSE

Protein
Submitted name:

Gamma-aminobutyric acid receptor subunit alpha-3

Gene

Gabra3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (08 Apr 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. extracellular ligand-gated ion channel activity Source: InterPro
    2. GABA-A receptor activity Source: InterPro

    GO - Biological processi

    1. chloride transport Source: InterPro
    2. gamma-aminobutyric acid signaling pathway Source: InterPro

    Keywords - Molecular functioni

    Ion channelUniRule annotationSAAS annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Gamma-aminobutyric acid receptor subunit alpha-3Imported
    Gene namesi
    Name:Gabra3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:95615. Gabra3.

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-KW
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: UniProtKB-KW
    4. synapse Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell junction, Cell membraneSAAS annotation, Membrane, SynapseSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiB1AVY2.

    Expressioni

    Gene expression databases

    ArrayExpressiB1AVY2.

    Structurei

    3D structure databases

    ProteinModelPortaliB1AVY2.
    SMRiB1AVY2. Positions 109-406.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00550000074441.
    HOGENOMiHOG000231337.
    HOVERGENiHBG051707.
    InParanoidiB1AVY2.
    OMAiASPKTTY.

    Family and domain databases

    Gene3Di2.70.170.10. 1 hit.
    InterProiIPR006028. GABAA/Glycine_rcpt.
    IPR001390. GABAAa_rcpt.
    IPR005433. GABBAa3_rcpt.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    [Graphical view]
    PANTHERiPTHR18945. PTHR18945. 1 hit.
    PfamiPF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 2 hits.
    [Graphical view]
    PRINTSiPR01079. GABAARALPHA.
    PR01616. GABAARALPHA3.
    PR00253. GABAARECEPTR.
    PR00252. NRIONCHANNEL.
    SUPFAMiSSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    TIGRFAMsiTIGR00860. LIC. 1 hit.
    PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1AVY2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEGREERKGG SSHFGPEERS KHLTAACTVD LTGLFKLLSK KMIITQMWHF    50
    YVTRVVLLLL ISILPGTTSQ GESRRQEPGD FVKQDIGGLS PKHAPDIPDD 100
    STDNITIFTR ILDRLLDGYD NRLRPGLGDA VTEVKTDIYV TSFGPVSDTD 150
    MEYTIDVFFR QTWHDERLKF DGPMKILPLN NLLASKIWTP DTFFHNGKKS 200
    VAHNMTTPNK LLRLVDNGTL LYTMRLTIHA ECPMHLEDFP MDVHACPLKF 250
    GSYAYTKAEV IYSWTLGKNK SVEVAQDGSR LNQYDLLGHV VGTEIIRSST 300
    GEYVVMTTHF HLKRKIGYFV IQTYLPCIMT VILSQVSFWL NRESVPARTV 350
    FGVTTVLTMT TLSISARNSL PKVAYATAMD WFIAVCYAFV FSALIEFATV 400
    NYFTKRSWAW EGKKVPEALE MKKKTPAAPT KKNTTFNIVG TTYPINLAKD 450
    TEFSTISKSA AAPSASSTPT AIASPKATYV QDSPAETKTY NSVSKVDKIS 500
    RIIFPVLFAI FNLVYWATYV NRESAIKGMI RKQ 533
    Length:533
    Mass (Da):59,912
    Last modified:April 8, 2008 - v1
    Checksum:i5B82129252D544CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL731695 Genomic DNA. No translation available.
    BX119994 Genomic DNA. No translation available.
    BX813327 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000114554; ENSMUSP00000110201; ENSMUSG00000031343.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL731695 Genomic DNA. No translation available.
    BX119994 Genomic DNA. No translation available.
    BX813327 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B1AVY2.
    SMRi B1AVY2. Positions 109-406.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B1AVY2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000114554 ; ENSMUSP00000110201 ; ENSMUSG00000031343 .

    Organism-specific databases

    MGIi MGI:95615. Gabra3.

    Phylogenomic databases

    GeneTreei ENSGT00550000074441.
    HOGENOMi HOG000231337.
    HOVERGENi HBG051707.
    InParanoidi B1AVY2.
    OMAi ASPKTTY.

    Miscellaneous databases

    NextBioi 35546107.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi B1AVY2.

    Family and domain databases

    Gene3Di 2.70.170.10. 1 hit.
    InterProi IPR006028. GABAA/Glycine_rcpt.
    IPR001390. GABAAa_rcpt.
    IPR005433. GABBAa3_rcpt.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    [Graphical view ]
    PANTHERi PTHR18945. PTHR18945. 1 hit.
    Pfami PF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 2 hits.
    [Graphical view ]
    PRINTSi PR01079. GABAARALPHA.
    PR01616. GABAARALPHA3.
    PR00253. GABAARECEPTR.
    PR00252. NRIONCHANNEL.
    SUPFAMi SSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    TIGRFAMsi TIGR00860. LIC. 1 hit.
    PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB1AVY2_MOUSE
    AccessioniPrimary (citable) accession number: B1AVY2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 8, 2008
    Last sequence update: April 8, 2008
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3