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B1AVY2

- B1AVY2_MOUSE

UniProt

B1AVY2 - B1AVY2_MOUSE

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Protein
Submitted name:

Gamma-aminobutyric acid receptor subunit alpha-3

Gene

Gabra3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. extracellular ligand-gated ion channel activity Source: InterPro
  2. GABA-A receptor activity Source: InterPro

GO - Biological processi

  1. chloride transport Source: InterPro
  2. gamma-aminobutyric acid signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Gamma-aminobutyric acid receptor subunit alpha-3Imported
Gene namesi
Name:Gabra3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:95615. Gabra3.

Subcellular locationi

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: UniProtKB-KW
  4. synapse Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, SynapseSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiB1AVY2.

Expressioni

Gene expression databases

ExpressionAtlasiB1AVY2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB1AVY2.
SMRiB1AVY2. Positions 106-521.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119010.
HOGENOMiHOG000231337.
HOVERGENiHBG051707.
OMAiASPKTTY.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiIPR006028. GABAA/Glycine_rcpt.
IPR001390. GABAAa_rcpt.
IPR005433. GABBAa3_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 2 hits.
[Graphical view]
PRINTSiPR01079. GABAARALPHA.
PR01616. GABAARALPHA3.
PR00253. GABAARECEPTR.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
TIGRFAMsiTIGR00860. LIC. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1AVY2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEGREERKGG SSHFGPEERS KHLTAACTVD LTGLFKLLSK KMIITQMWHF
60 70 80 90 100
YVTRVVLLLL ISILPGTTSQ GESRRQEPGD FVKQDIGGLS PKHAPDIPDD
110 120 130 140 150
STDNITIFTR ILDRLLDGYD NRLRPGLGDA VTEVKTDIYV TSFGPVSDTD
160 170 180 190 200
MEYTIDVFFR QTWHDERLKF DGPMKILPLN NLLASKIWTP DTFFHNGKKS
210 220 230 240 250
VAHNMTTPNK LLRLVDNGTL LYTMRLTIHA ECPMHLEDFP MDVHACPLKF
260 270 280 290 300
GSYAYTKAEV IYSWTLGKNK SVEVAQDGSR LNQYDLLGHV VGTEIIRSST
310 320 330 340 350
GEYVVMTTHF HLKRKIGYFV IQTYLPCIMT VILSQVSFWL NRESVPARTV
360 370 380 390 400
FGVTTVLTMT TLSISARNSL PKVAYATAMD WFIAVCYAFV FSALIEFATV
410 420 430 440 450
NYFTKRSWAW EGKKVPEALE MKKKTPAAPT KKNTTFNIVG TTYPINLAKD
460 470 480 490 500
TEFSTISKSA AAPSASSTPT AIASPKATYV QDSPAETKTY NSVSKVDKIS
510 520 530
RIIFPVLFAI FNLVYWATYV NRESAIKGMI RKQ
Length:533
Mass (Da):59,912
Last modified:April 8, 2008 - v1
Checksum:i5B82129252D544CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL731695 Genomic DNA. No translation available.
BX119994 Genomic DNA. No translation available.
BX813327 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000114554; ENSMUSP00000110201; ENSMUSG00000031343.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL731695 Genomic DNA. No translation available.
BX119994 Genomic DNA. No translation available.
BX813327 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B1AVY2.
SMRi B1AVY2. Positions 106-521.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B1AVY2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000114554 ; ENSMUSP00000110201 ; ENSMUSG00000031343 .

Organism-specific databases

MGIi MGI:95615. Gabra3.

Phylogenomic databases

GeneTreei ENSGT00760000119010.
HOGENOMi HOG000231337.
HOVERGENi HBG051707.
OMAi ASPKTTY.

Miscellaneous databases

NextBioi 35546107.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi B1AVY2. baseline and differential.

Family and domain databases

Gene3Di 2.70.170.10. 1 hit.
InterProi IPR006028. GABAA/Glycine_rcpt.
IPR001390. GABAAa_rcpt.
IPR005433. GABBAa3_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view ]
PANTHERi PTHR18945. PTHR18945. 1 hit.
Pfami PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 2 hits.
[Graphical view ]
PRINTSi PR01079. GABAARALPHA.
PR01616. GABAARALPHA3.
PR00253. GABAARECEPTR.
PR00252. NRIONCHANNEL.
SUPFAMi SSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
TIGRFAMsi TIGR00860. LIC. 1 hit.
PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB1AVY2_MOUSE
AccessioniPrimary (citable) accession number: B1AVY2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3