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Protein

Matrix metalloproteinase

Gene

Mmp16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Ca2+UniRule annotation
  • Zn2+UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Matrix metalloproteinaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:Mmp16Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1276107 Mmp16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

ZymogenUniRule annotation

Proteomic databases

PRIDEiB1AVH0

Expressioni

Gene expression databases

BgeeiENSMUSG00000028226
ExpressionAtlasiB1AVH0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB1AVH0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 67PG_binding_1InterPro annotationAdd BLAST51
Domaini97 – 173Peptidase_M10InterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the peptidase M10A family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1565 Eukaryota
ENOG410XQ5D LUCA
GeneTreeiENSGT00760000118870
HOGENOMiHOG000239471

Family and domain databases

Gene3Di3.40.390.10, 1 hit
InterProiView protein in InterPro
IPR024079 MetalloPept_cat_dom_sf
IPR028697 MMP16
IPR001818 Pept_M10_metallopeptidase
IPR021190 Pept_M10A
IPR021158 Pept_M10A_Zn_BS
IPR002477 Peptidoglycan-bd-like
IPR036365 PGBD-like_sf
PANTHERiPTHR10201:SF26 PTHR10201:SF26, 1 hit
PfamiView protein in Pfam
PF00413 Peptidase_M10, 1 hit
PF01471 PG_binding_1, 1 hit
PRINTSiPR00138 MATRIXIN
SUPFAMiSSF47090 SSF47090, 1 hit
PROSITEiView protein in PROSITE
PS00546 CYSTEINE_SWITCH, 1 hit

Sequencei

Sequence statusi: Fragment.

B1AVH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGEVTQALG GAQKIVWLQK YGYLPPTDPR MSVLRSAETM QSALAAMQQF
60 70 80 90 100
YGINMTGKVD RNTIDWMKKP RCGVPDQTRG SSKFNIRRKR YALTGQKWQH
110 120 130 140 150
KHITYSIKNV TPKVGDPETR RAIRRAFDVW QNVTPLTFEE VPYSELENGK
160 170
RDVDITIIFA SGFHGDSSPF DGEG
Length:174
Mass (Da):19,713
Last modified:April 8, 2008 - v1
Checksum:i2465173B6E68C5E2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei174Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL683877 Genomic DNA No translation available.
AL805957 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000149353; ENSMUSP00000116930; ENSMUSG00000028226

Similar proteinsi

Entry informationi

Entry nameiB1AVH0_MOUSE
AccessioniPrimary (citable) accession number: B1AVH0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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