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Protein

Matrix metalloproteinase

Gene

Mmp16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Ca2+UniRule annotation
  • Zn2+UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Matrix metalloproteinaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:Mmp16Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1276107 Mmp16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

ZymogenUniRule annotation

Proteomic databases

PRIDEiB1AVG8

Expressioni

Gene expression databases

BgeeiENSMUSG00000028226
ExpressionAtlasiB1AVG8 baseline and differential

Structurei

3D structure databases

SMRiB1AVG8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 96PG_binding_1InterPro annotationAdd BLAST54

Sequence similaritiesi

Belongs to the peptidase M10A family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1565 Eukaryota
ENOG410XQ5D LUCA
GeneTreeiENSGT00760000118870

Family and domain databases

Gene3Di1.10.101.10, 1 hit
InterProiView protein in InterPro
IPR028697 MMP16
IPR021158 Pept_M10A_Zn_BS
IPR002477 Peptidoglycan-bd-like
IPR036365 PGBD-like_sf
IPR036366 PGBDSf
PANTHERiPTHR10201:SF26 PTHR10201:SF26, 1 hit
PfamiView protein in Pfam
PF01471 PG_binding_1, 1 hit
SUPFAMiSSF47090 SSF47090, 1 hit
PROSITEiView protein in PROSITE
PS00546 CYSTEINE_SWITCH, 1 hit

Sequencei

Sequence statusi: Fragment.

B1AVG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILLAFSSGR RLDFVHRSGV FFLQTLLWIL CATVCGTEQY FNVEVWLQKY
60 70 80 90 100
GYLPPTDPRM SVLRSAETMQ SALAAMQQFY GINMTGKVDR NTIDWMKKPR
110 120
CGVPDQTRGS SKFNIRRKRY ALTGQKW
Length:127
Mass (Da):14,722
Last modified:April 8, 2008 - v1
Checksum:i9C8D1A90358846E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei127Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL683877 Genomic DNA No translation available.
AL805957 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000142434; ENSMUSP00000121087; ENSMUSG00000028226

Similar proteinsi

Entry informationi

Entry nameiB1AVG8_MOUSE
AccessioniPrimary (citable) accession number: B1AVG8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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