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Protein

Matrix metalloproteinase

Gene

Mmp16

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Ca2+UniRule annotation
  • Zn2+UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Matrix metalloproteinaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:Mmp16Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1276107. Mmp16.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Keywords - PTMi

ZymogenUniRule annotation

Proteomic databases

PaxDbiB1AVG8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028226.
ExpressionAtlasiB1AVG8. baseline and differential.

Structurei

3D structure databases

SMRiB1AVG8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 96PG_binding_1InterPro annotationAdd BLAST54

Sequence similaritiesi

Belongs to the peptidase M10A family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1565. Eukaryota.
ENOG410XQ5D. LUCA.
GeneTreeiENSGT00760000118870.

Family and domain databases

Gene3Di3.40.390.10. 1 hit.
InterProiView protein in InterPro
IPR024079. MetalloPept_cat_dom.
IPR028697. MMP16.
IPR021158. Pept_M10A_Zn_BS.
IPR002477. Peptidoglycan-bd-like.
PANTHERiPTHR10201:SF168. PTHR10201:SF168. 1 hit.
PfamiView protein in Pfam
PF01471. PG_binding_1. 1 hit.
SUPFAMiSSF47090. SSF47090. 1 hit.
PROSITEiView protein in PROSITE
PS00546. CYSTEINE_SWITCH. 1 hit.

Sequencei

Sequence statusi: Fragment.

B1AVG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILLAFSSGR RLDFVHRSGV FFLQTLLWIL CATVCGTEQY FNVEVWLQKY
60 70 80 90 100
GYLPPTDPRM SVLRSAETMQ SALAAMQQFY GINMTGKVDR NTIDWMKKPR
110 120
CGVPDQTRGS SKFNIRRKRY ALTGQKW
Length:127
Mass (Da):14,722
Last modified:April 8, 2008 - v1
Checksum:i9C8D1A90358846E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei127Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL683877 Genomic DNA. No translation available.
AL805957 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000142434; ENSMUSP00000121087; ENSMUSG00000028226.

Similar proteinsi

Entry informationi

Entry nameiB1AVG8_MOUSE
AccessioniPrimary (citable) accession number: B1AVG8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 8, 2008
Last sequence update: April 8, 2008
Last modified: August 30, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported